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延边地区丙型肝炎患者合并TT病毒感染的检测
引用本文:齐栋,张永芬,范华英,李红花,魏成淑,李辉,李英信,孟繁平.延边地区丙型肝炎患者合并TT病毒感染的检测[J].微生物学杂志,2004,24(5):108-110.
作者姓名:齐栋  张永芬  范华英  李红花  魏成淑  李辉  李英信  孟繁平
作者单位:1. 延边大学,医学院微生物学与免疫学教研室,吉林,延吉,133000
2. 延边大学,医学院附属医院检验科,吉林,延吉,133000
摘    要:检测丙型肝炎患者血清标本中的TT病毒 (transfusiontransmittedvirus,TTV) ,了解延边地区丙型肝炎患者合并TTV感染状况。采用ELISA检测抗TTVIgG和巢式PCR检测丙型肝炎病毒 (HCV)感染患者血清中TTVDNA。采用全自动生化分析仪检测患者血清谷氨酸氨基转移酶 (ALT)和谷氨酸草酰乙酸氨基转移酶 (AST)。 4 5例丙型肝炎患者抗TTVIgG阳性率为 37.8% (17/45 ) ,巢式PCR阳性率为 4 2 .2 % (19/45 )。延边地区HCV感染患者重叠感染TTV较常见。

关 键 词:输血传播病毒  丙型肝炎
文章编号:1005-7021(2004)05-0108-03
修稿时间:2004年5月15日

Co-infection of Transfusion Transmitted Virus in the Patients with Hepatitis C in Yanbian Area
QI Dong,ZHANG Yongfen,FAN Huaying,LI Honghua,WEI Chengshu,LI Hui,LI Yingxin,MENG Fanping.Co-infection of Transfusion Transmitted Virus in the Patients with Hepatitis C in Yanbian Area[J].Journal of Microbiology,2004,24(5):108-110.
Authors:QI Dong  ZHANG Yongfen  FAN Huaying  LI Honghua  WEI Chengshu  LI Hui  LI Yingxin  MENG Fanping
Institution:QI Dong1,ZHANG Yongfen2,FAN Huaying1,LI Honghua1,WEI Chengshu1,LI Hui1,LI Yingxin1,MENG Fanping1
Abstract:Transfusion transmitted virus (TTV) in hepatitis C patients in Yanbian area was detected to determine the coinfection frequency of TTV and HCV in the patients. ELISA and nested PCR were used to examine anti-TTV IgG and TTV DNA in the serum samples, respectively. The levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in the serum samples were measured by using AutoBiochemistry Analyzer. In the samples from 45 hepatitis C patients, the anti-TTV IgG positive rate was 37.8 % (17/45) while the TTV DNA positive rate was 42.2 % (19/45), indicating the frequent TTV infection in the hepatitis C patients in Yanbian area.;
Keywords:transfusion transmitted Virus  Hepatitis C  
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