| 近5年美国FDA批准上市的含氟药物研究进展 |
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| 引用本文： | 刘栓栓#.近5年美国FDA批准上市的含氟药物研究进展[J].微生物学杂志,2016(10). |
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| 作者姓名： | 刘栓栓# |
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| 作者单位： | 南京工业大学药学院，江苏 南京 210009 |
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| 摘 要： | 将氟原子引入药物分子中是药物改性的重要策略之一，有助于改善其物理化学特性。随着对氟化学、含氟基团的研究进展，含氟药物在临床治疗药物中占有相当的比重。概述近年来美国FDA 批准上市的含氟药物的最新研究成果。
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| 关 键 词： | 新药 氟 新化学实体 含氟药物 |
Recent Advances in R&D of Fluorinated Drugs Approved by FDA in the Past Five Years |
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| LIU Shuanshuan.Recent Advances in R&D of Fluorinated Drugs Approved by FDA in the Past Five Years[J].Journal of Microbiology,2016(10). |
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| Authors: | LIU Shuanshuan |
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| Institution: | College of Pharmacy, Nanjing Tech University, Nanjing 210009, China |
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| Abstract: | Introduction of fluorine-containing groups is an important strategy to alter the properties of chemical drugs. With advances in the study of fluorine chemistry and fluorine-containing groups, fluorine-containing drugs account for a considerable proportion of therapeutic drugs. This review outlines the recent advances in fluorinated drugs approved by FDA in the past five years |
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| Keywords: | new drug fluorine new chemical entity fluorine-containing drug |
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