| 柯萨奇B组病毒感染与胰岛素依赖型糖尿病关系的研究 |
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| 引用本文： | 黄红兰,李凡.柯萨奇B组病毒感染与胰岛素依赖型糖尿病关系的研究[J].微生物学杂志,2003,23(6):5-6. |
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| 作者姓名： | 黄红兰 李凡 |
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| 作者单位： | 吉林大学,基础医学院病原生物学教研室,吉林,长春,130021 |
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| 摘 要： | 探讨柯萨奇B组病毒(CBV)感染与胰岛素依赖型糖尿病之间的关系。用PT-PCR方法检测38例IDDM患者外周血中CBV-RNA,同时用ELISA法测定血清中CBV特异性IgM。结果显示,病例组38例患者外周血CBV-RNA阳性率为42.10％,血清中CBV-IgM阳性率为36.84％。对照组的阳性率分别为7.5％和5％。两组比较有显著性差别(P<0.05)。说明胰岛素依赖型糖尿病与柯萨奇B组病毒感染有关。
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| 关 键 词： | 胰岛素依赖型糖尿病 柯萨奇B组病毒 RT-PCR IgM抗体 |
| 文章编号： | 1005-7021(2003)06-0005-02 |
| 修稿时间： | 2003年2月25日 |
A Study on the Relationship Between Coxsackie B Virus Infection and Insulin Dependent Diabetes Mellitus |
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| HUANG Honglan.LI Fan.A Study on the Relationship Between Coxsackie B Virus Infection and Insulin Dependent Diabetes Mellitus[J].Journal of Microbiology,2003,23(6):5-6. |
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| Authors: | HUANG HonglanLI Fan |
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| Abstract: | To study the relationship between coxsackie B virus infection and Insulin dependent diabetes mellitus, CBV-RNA in peripheral blood cells and CBV-IgM in sera of 38 patients with IDDM were detected by RT-PCR and ELISA respectively. The Results showed that IDDM patien's positive rates of CBV-RNA in peripheral blood cells and CBV-IgM in sera were 42.10% and 36.84% .respectively,Which showed significant difference compared with controlled group(P<0.05).These results suggested that coxsackie B virus infection and Insulin dependent diabetes mellitus were correlated. |
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| Keywords: | Insulin dependent diabetes meliitus coxsackie B virus RT-PCR IgM |
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