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Preliminary study on the phytochemical evolution of different Lamiaceae species based on iridoids
Institution:1. Dipartimento di Biologia Ambientale, Piazzale Aldo Moro, 5, 00185, Rome, Italy;2. Dipartimento di Chimica: Università di Roma “La Sapienza”, Piazzale Aldo Moro, 5, 00185, Rome, Italy;3. Dipartimento di Scienze Farmaceutiche: Università degli Studi di Milano, Via Mangiagalli 25, I-20133, Milano, Italy;4. School of Pharmacy: University of Camerino, Via S. Agostino, 1 - 62032, Camerino, Italy;1. Key Laboratory of Marine Biogenetic Resources, South China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center, Third Institute of Oceanography, Ministry of Natural Resources, 184 Daxue Road, Xiamen, 361005, China;2. Yanjing Medical College, Capital Medical University, 4 Dadong Road, Beijing, 101300, China;1. Department of Plant Protection, University of Life Sciences in Lublin, Leszczyńskiego 7, 20-069, Lublin, Poland;2. Department of Biochemistry and Molecular Biology, Siedlce University of Natural Sciences and Humanities, Prusa 12, 08-110, Siedlce, Poland;3. Department of Molecular Biotechnology, Faculty of Biotechnology, University of Rzeszów, Pigonia 1, 35-310, Rzeszów, Poland;1. State Key Laboratory of Innovative Drugs and High Efficiency Energy Saving and Consumption Reduction Pharmaceutical Equipment, Research Center of Natural Resources of Chinese Medicinal Materials and Ethnic Medicine, Key Laboratory of Modern Preparation of TCM of Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang, 330004, China;2. College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang, 473061, China;1. Université de Corse - CNRS, UMR 6134 SPE, Equipe Chimie et Biomasse, Route des Sanguinaires, 20000, Ajaccio, France;2. Neuchâtel Platform of Analytical Chemistry, University of Neuchâtel, Avenue de Bellevaux 51, 2000, Neuchâtel, Switzerland;1. School of Pharmacy, Kumamoto University, 5-1 Oe-honmachi, Chuo ku, Kumamoto, 862-0973, Japan;2. Program for Leading Graduate Schools, Health Life Science: Interdisciplinary and Glocal Oriented (HIGO) Program, Kumamoto University, Kumamoto, Japan
Abstract:In this work, an interesting potential application of phytochemistry is reported. In particular, we employed the Sporne diagrams to provide information about the evolution of some different Lamiaceae species in relation to their content in secondary metabolites. In more details, fifteen species belonging to six different genera were studied i.e. Ajuga L., Galeopsis L., Melittis L., Sideritis L., Stachys L. and Teucrium L. The selected secondary metabolites were iridoids because of their wide occurrence and distribution within all the family, thus providing a more accurate and general overview. Nineteen different compounds of this class were identified in the studied species. The aim of this work was to verify if the evolutionary data available in literature for the studied species and based on molecular studies, matched with those obtained from a more phytochemical approach or not. The final objective was to ascertain a correspondence between these two opposite methods. The results of this study clearly showed that, only in some cases, this correspondence was present. This may suggest the possibility to use both methods for drawing phylogenetic trees of plants. Anyway, this study is not general and is quite limited in studied species and in collection areas and does not intend to affirm its absolute accuracy even though it may be a good starting point for future researches in this field.
Keywords:Lamiaceae  Phytochemistry  Iridoids  Evolution  Sporne diagrams
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