Chemical constituents from Picrasma quassioides (D.Don) Benn. and their network analysis of chemotaxonomic significance |
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| Institution: | 1. School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, People’s Republic of China;2. School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, People’s Republic of China;3. Chinese People''s Liberation Army 210 Hospital, Dalian 116021, People’s Republic of China |
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| Abstract: | A phytochemical investigation of Picrasma quassioides (D.Don) Benn led to the isolation of seventeen compounds including five coumarins (1–5), six lignans (6–11), two alkaloids (12–13), two phenolic compounds (14–15), one megastigman glycoside (16) and one phenylpropanoid (17). The structures of those compounds were determined by spectroscopy data of NMR spectra. All of the compounds were isolated from P. quassioides for the first time. In this study, in order to discuss the chemotaxonomic significance of those compounds from P. quassioides, network analysis was carried out to determine the chemotaxonomic relationships among the Simaroubaceae family and the other families. The result showed that the Simaroubaceae family and the Rutaceae family, together with the Asteraceae family have some chemotaxonomic relationships. |
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| Keywords: | Coumarins Triterpenes Alkaloids Lignans Chemotaxonomic |
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