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Chemical constituents from the roots of Fallopia multiflora var. Ciliinerve
Institution:1. School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, China;2. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, BeiJing, 100700, China;3. Shaanxi Institute of International Trade & Commerce, Xianyang, 712046, China;1. Department of Pharmacognosy, Faculty of Pharmacy, Medical University-Sofia, 2 Dunav Str., 1000, Sofia, Bulgaria;2. Department of Biology, Science Faculty, Selcuk University, Konya, Turkey;3. Department of Chemistry, Faculty of Pharmacy, Medical University-Sofia, 2 Dunav Str., 1000, Sofia, Bulgaria;1. Faculty of Agriculture, Iwate University, Morioka, 020-8550, Japan;2. Agri-Innovation Center, Iwate University, Morioka, 020-8550, Japan;3. Faculty of Humanities & Social Science, Iwate University, Morioka, 020-8550, Japan;4. Faculty of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, 183-8509, Japan;1. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, PR China;2. Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, 110032, PR China;1. School of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang, 330004, People′s Republic of China;2. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, People′s Republic of China;1. Department of Chemistry, Science College, Princess Nourah Bint Abdulrahman University, Riyadh, 11671, Saudi Arabia;2. Department of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh, 11451, Saudi Arabia;3. Pharmacognosy Department, Faculty of Pharmacy, Mansoura University, El Mansoura, 35516, Egypt;4. Pharmacognosy Department, Faculty of Pharmacy, Assiut University, Assiut, 71526, Egypt;5. Department of Pharmacognosy, College of Pharmacy, Prince Sattam bin Abdulaziz University, Al-kharj, 11942, Saudi Arabia;6. Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University, Alexandria, 21215, Egypt
Abstract:Phytochemical investigations on the roots of Fallopia multiflora var. Ciliinerve led to the isolation of eighteen compounds, including six chromones 2-methyl-5- carboxymethyl-7-hydroxychromone (1), 2-methyl-5-methylcarboxymethyl-7- hydroxychromone (2), 2,5-dimethyl-7-hydroxychromone (3), 2-methyl-5-hydroxymeth-yl-7-hydroxychromone (4), 2-methyl-5-carboxylicacid-7-hydroxy-chromone (5), and 2,5-dimethyl-7-hydroxychromone-7-O-β-D-glucopyranoside (6)], three lignans Isolariciresinol (8), 5-4-(3,4-dimethoxyphenyl)-2,3-dimethylbutyl]-1,3-benzodioxole (9), and isolariciresinol-9-O-β-D-xylopyranoside (10)], four anthraquinones physcion-8-O-β-D-glucopyranoside (11), emodin-8-O-β-D-glucopyranoside (12), Rhein (13), and Chrysophanol (14)], three isobenzofurans 5,7-dihydroxy-isobenzofuran (15), 5-methoxy-7-hydroxy-isobenzofuran (16), and 5-methoxy-isobenzofuran-7-O-β-D-glucoside (17)], one phenolic acid 2,5-diacethylhy-droquinone (7)], and one pyran Zanthopyranone (18)]. Among them, compounds 1, 3, 6, 13 and 14 were reported from F. multiflora var. Ciliinerve for the first time, compounds 2, 8, 10 and 15–17 were isolated from the genus Fallopia for the first time, and compounds 4, 9 and 18 were isolated for the first time from Polygonaceae family. Furthermore, the isolation of compounds 5 and 7 were reported for the first time in plants. Their structures were identified by spectroscopic methods and compared with those previously published. The chemotaxonomic significance of these isolated compounds has also been discussed.
Keywords:Polygonaceae  Chemotaxonomy
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