Genetic control of the quantitative variation of erythrocytic glyoxalase-1 (GLO-1) in mice |
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Authors: | Pablo Rubinstein Katalin Vienne |
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Institution: | (1) Immunogenetics, The Lindsley F. Kimball Research Institute of The New York Blood Center, 10021 New York, New York |
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Abstract: | Quantitative genetic variation in the glyoxalase-1 content (QGlo-1) of red cells of mice is described. Its genetic control is shown to be exerted by either the Glo-1 locus or a closely linked gene to the left of H-2K. At least six alleles, designated QGlo-1
a through QGlo-1
f, can be found in different inbred strains of mice.This work was supported in part by Grants HL 0911 and AI 15413 of the National Institutes of Health and by a grant from the Sally and Alma Solomon Foundation. |
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Keywords: | glyoxalase-1 genetics quantitative polymorphism major histocompatibility system linkage |
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