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| 灰树花提取物清除氧自由基的研究 | |
| 引用本文： | 周昌艳,唐庆九,王军,刘峻,杨焱.灰树花提取物清除氧自由基的研究[J].菌物研究,2006,4(3):31-34. |
| 作者姓名： | 周昌艳 唐庆九 王军 刘峻 杨焱 |
| 作者单位： | 1. 上海市农业科学院食用菌研究所,上海,201106 2. 安徽中医学院,安徽,合肥,230031 3. 中国药科大学,江苏,南京,210009 |
| 基金项目： | 上海市科学技术委员会攻关项目(013912048) |
| 摘 要： | 采用化学发光法比较了灰树花各提取物对超氧阴离子自由基、羟基自由基的清除效果。研究结果表明,灰树花子实体和菌丝体的提取物对羟基自由基均有很好的清除作用,灰树花菌丝体水提物(GFME)、灰树花子实体水提物(GFE)、灰树花子实体水提多糖(GFP)、灰树花子实体碱提多糖(GFAP)清除羟基自由基的IC50均小于1.0 mg/mL,其他提取物清除羟基自由基的IC50也均小于3.0 mg/mL。而对超氧阴离子自由基仅GFME、GFMP、GFE有清除作用,其他的提取物清除作用很弱。 |
| 关 键 词： | 灰树花提取物 超氧阴离子自由基 羟基自由基 |
| 文章编号： | 1672-3538（2006）03-0031-04 |
| 修稿时间： | 2006年7月15日 |
Scavenging Effects of Extracts of Grifola frondosa on Active Oxygen Radicals |
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| ZHOU Chang-yan,TANG Qing-jiu,WANG Jun,LIU Jun,YANG Yan.Scavenging Effects of Extracts of Grifola frondosa on Active Oxygen Radicals[J].Journal of Fungal Research,2006,4(3):31-34. | |
| Authors: | ZHOU Chang-yan TANG Qing-jiu WANG Jun LIU Jun YANG Yan |
| Abstract: | The chemiluminesence method was used to detect the effect of the extracts of Grifola frondosa on scavenging OH· and O~-_2.The research result shows that the extracts of G.frondosa fruit body and mycelia have an expected capacity of scavenging OH·.The IC_(50)s of water extraction of G.frondosa mycelia(GFME),water extraction of G.frondosa fruit body (GFE),the polysaccharide of G.frondosa fruit body(GFP) and alkaline-extracted polysaccharide of G.frondosa(GFAP) on scavenging OH· were less than 1.0 mg/mL,while the IC_(50)s of other extractions of G.frondosa were all less than 3.0 mg/mL.GFME,GFMP and GFE possessed the effect of scavenging O~-_2,but the other extractions of G.frondosa didn′t show evident effect. |
| Keywords: | extracts of Grifola frondosa O_2~- free radical OH·free radical |
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