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Initial hydrodynamic study on a new intraaortic axial flow pump: Dynamic aortic valve
作者姓名:李国荣  赵红  胡盛寿  朱晓东  吴清玉  任兵  马维国
作者单位:LI Guorong ZHAO Hong HU ShengshouZHU Xiaodong WU Qingyu REN Bing& MA WeiguoDivision of Assisted Circulation & Heart Valve,Department of Cardiac Surgery,Fuwai Heart Hospital & Cardiovascular Institute,Peking Union Medical College,Chinese Academy of Medical Sciences,Beijing 100037,China
基金项目:the National Natural Science Foundation of China (Grant No. 39870732).
摘    要:Rotary blood pumps have been researched as implantable ventricular assist devices for years. To further reduce the complex of implanted axial pumps, the authors proposed a new concept of intraaortic axial pump, termed previously as "dynamic aortic valve (DAV)". Instead of being driven by an intraaortic micro-electric motor, it was powered by a magnetic field from outside of body. To ensure the perfusion of coronary artery, the axial flow pump is to be implanted in the position of aortic valve. It could serve as either a blood pump or a mechanical valve depending on the power input. This research tested the feasibility of the new concept in model study. A column, made from permanent magnet, is jointed to an impeller in a concentric way to form a "rotor-impeller". Supported by a hanging shaft cantilevered in the center of a rigid cage, the rotor-impeller can be turned by the magnetic field in the surrounding space. In the present prototype, the rotor is 8 mm in diameter and 15 mm in length, the impeller ha

收稿时间:6 July 2000

Initial hydrodynamic study on a new intraaortic axial flow pump: Dynamic aortic valve
Guorong Li,Hong Zhao,Shengshou Hu,Xiaodong Zhu,Qingyu Wu,Bing Ren,Weiguo Ma.Initial hydrodynamic study on a new intraaortic axial flow pump: Dynamic aortic valve[J].Science China Life sciences,2001,44(2):199-206.
Authors:Guorong Li  Hong Zhao  Shengshou Hu  Xiaodong Zhu  Qingyu Wu  Bing Ren  Weiguo Ma
Institution:(1) Division of Assisted Circulation & Heart Valve, Department of Cardiac Surgery, Fuwai Heart Hospital & Cardiovascular Institute, Peking Union Medical College, Chinese Academy of Medical Sciences, 100037 Beijing, China
Abstract:Rotary blood pumps have been researched as implantable ventricular assist devices for years. To further reduce the complex of implanted axial pumps, the authors proposed a new concept of intraaortic axial pump, termed previously as "dynamic aortic valve (DAV)". Instead of being driven by an intraaortic micro-electric motor, it was powered by a magnetic field from outside of body. To ensure the perfusion of coronary artery, the axial flow pump is to be implanted in the position of aortic valve. It could serve as either a blood pump or a mechanical valve depending on the power input. This research tested the feasibility of the new concept in model study. A column, made from permanent magnet, is jointed to an impeller in a concentric way to form a "rotor-impeller". Supported by a hanging shaft cantilevered in the center of a rigid cage, the rotor-impeller can be turned by the magnetic field in the surrounding space. In the present prototype, the rotor is 8 mm in diameter and 15 mm in length, the impeller has 3 vanes with an outer diameter of 18 mm. The supporting cage is 22 mm in outer diameter and 20 mm in length. When tested, the DAV prototype is inserted into the tube of a mock circuit. The alternative magnetic field is produced by a rotating magnet placed side by side with the rotor-impeller at a distance of 30 mm. Once the alternative magnetic field is presented in the surrounding space, the DAV starts to turn, leading to a pressure difference and liquid flow in the tube. The flow rate or pressure difference is proportioned to rotary speed. At the maximal output of hydraulic power, the flow rate reached 5 L/min against an afterload of 100 mmHg. The maximal pressure difference generated by DAV at a rotation rate of 12600 r/min was 147 mmHg. The preliminary results demonstrated the feasibility of "DAV", further research on this concept is justifiable.
Keywords:rotary blood pump  left ventricular assist device  dynamic aortic valve  valvo-pump  
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