Enrichment of AT-TA transversion at 5′-CAG-3′ motif is not a unique mutational signature of aristolochic acid Enrichment of AT-TA transversion at 5′-CAG-3′ motif is not a unique mutational signature of aristolochic acid期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Enrichment of AT-TA transversion at 5′-CAG-3′ motif is not a unique mutational signature of aristolochic acid

摘要：	<正>Aristolochic acids, mutational signature, and hepatocellular carcinoma Aristolochic acids (AA) are the etiologic agents of aristolochic acid nephropathy (AAN) and contribute to the global prevalence of chronic kidney disease and urothelial cancer (Grollman et al., 2007). DNA adducts formed by AA generate a unique AT transversions mutation spectrum at
Enrichment of AT-TA transversion at 5′-CAG-3′ motif is not a unique mutational signature of aristolochic acid

Authors:	Wang Xin Qi Xinming Ren Jin

Abstract:	Science China Life Sciences -

Keywords:
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