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The origin of a novel kind of reassortant (H1N2) of influenza A virus
作者姓名:郭元吉  祁俊林  孔利群  程小雯  董婕  王敏  张烨  郭俊峰  吴昆昱
作者单位:Institute of Virology,Chinese Academy of Preventive Medicine,Beijing 100052,China,Institute of Virology,Chinese Academy of Preventive Medicine,Beijing 100052,China,Centers for Diseases Control and Prevention of Shanghai,Shanghai 200031,China,Municipal Hygiene and Anti-epidemic Station of Shenzhen,Shenzhen 580020,China,Institute of Virology,Chinese Academy of Preventive Medicine,Beijing 100052,China,Institute of Virology,Chinese Academy of Preventive Medicine,Beijing 100052,China,Institute of Virology,Chinese Academy of Preventive Medicine,Beijing 100052,China,Institute of Virology,Chinese Academy of Preventive Medicine,Beijing 100052,China,Institute of Virology,Chinese Academy of Preventive Medicine,Beijing 100052,China
摘    要:Genetic analysis of three H1N2 viruses indicated that only HA genes of H1N2 viruses were similar to that of A/Guangdong/6/91(H1N1) virus (PR8-like strain), while the other seven genes of them were similar to those of H3N2 virus circulating in man in 1995. Therefore, it could be considered that the H1N2 viruses were derived from reassortment between PR8-like strain and H3N2 virus circulating in man in 1995. However, the genomes of H1N2 viruses were very similar to each other. So the H1N2 viruses isolated in 1998 were not derived from new reassortment between PR8-like strain and H3N2 virus circulating in man in 1998, but derived from the evolution of H1N2 virus found in 1995.

收稿时间:2000-02-18

The origin of a novel kind of reassortant (H1N2) of influenza A virus
GUO Yuanji QI Junlin KONG Liqun CHENG Xiaowen DONG Jie WANG Min ZHANG YeGUO Junfeng &,WU Kunyu.The origin of a novel kind of reassortant (H1N2) of influenza A virus[J].Science China Life sciences,2000,43(5):519-525.
Authors:GUO Yuanji QI Junlin KONG Liqun CHENG Xiaowen DONG Jie WANG Min ZHANG YeGUO Junfeng &  WU Kunyu
Institution:(1)Institute of Virology, Chinese Academy of Preventive Medicine, Beijing 100052 ,China (2) Centers for Diseases Controi and Prevention of Shanghai,Shanghai 200031,china (3)Municipal Hygiene and Anti-epidemic Station of Shenzhen, Shenzhen 580020 china
Abstract:Genetic analysis of three H1N2 viruses indicated that only HA genes of H1N2 viruses were similar to that of A/Guangdong/6/91(H1N1) virus (PR8-like strain), while the other seven genes of them were similar to those of H3N2 virus circulating in man in 1995. Therefore, it could be considered that the H1N2 viruses were derived from reassortment between PR8-like strain and H3N2 virus circulating in man in 1995. However, the genomes of H1N2 viruses were very similar to each other. So the H1N2 viruses isolated in 1998 were not derived from new reassortment between PR8-like strain and H3N2 virus circulating in man in 1998, but derived from the evolution of H1N2 virus found in 1995.
Keywords:influenza A virus  a novel kind of reassortant  origin  
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