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Dynamic Role of the G Protein in Stabilizing the Active State of the Adenosine A2A Receptor
Authors:Sangbae Lee  Anita K Nivedha  Christopher G Tate  Nagarajan Vaidehi
Institution:1. Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, 1500 E. Duarte Road, Duarte, CA 91010, USA;2. MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, Cambridge CB2 0QH, UK
Abstract:
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  • Keywords:G protein-coupled receptors (GPCRs)  molecular dynamics simulations  adenosine receptor  ligand mobility  entropy  allosteric communication
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