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The Structural Basis of the Farnesylated and Methylated KRas4B Interaction with Calmodulin
Authors:Hyunbum Jang  Avik Banerjee  Kendra Marcus  Lee Makowski  Carla Mattos  Vadim Gaponenko  Ruth Nussinov
Institution:1. Computational Structural Biology Section, Basic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA;2. Department of Chemistry, University of Illinois at Chicago, Chicago, IL 60607, USA;3. Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA;4. Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL 60607, USA;5. Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
Abstract:
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  • Keywords:Corresponding author  post-translational modifications  farnesylation and methylation  phosphatidylinositol  NMR  MD simulation  SAXS  PI3K  hypervariable region
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