|
|||||
|
|
Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity |
|
| Authors: | Takehiko Oka Yuhei Nishimura Minoru Hirano Yasuhito Shimada Noriko Umemoto Junya Kuroyanagi Norihiro Nishimura " target="_blank">Toshio Tanaka |
| Institution: | (1) Department of Molecular and Cellular Pharmacology, Pharmacogenomics and Pharmacoinformatics, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu Mie, 514-8507, Japan;(2) Department of Bioinformatics, Mie University Life Science Research Center, 2-174 Edobashi, Tsu Mie, 514-8507, Japan;(3) Department of Medical Chemogenomics, Mie University Venture Business Laboratory, 2-174 Edobashi, Tsu Mie, 514-8507, Japan;(4) Mie University Medical Zebrafish Research Center, 2-174 Edobashi, Tsu Mie, 514-8507, Japan;(5) Department of Translational Medical Science, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu Mie, 514-8507, Japan |
| Abstract: | BackgroundObesity is a multifactorial disorder influenced by genetic and environmental factors. Animal models of obesity are required to help us understand the signaling pathways underlying this condition. Zebrafish possess many structural and functional similarities with humans and have been used to model various human diseases, including a genetic model of obesity. The purpose of this study was to establish a zebrafish model of diet-induced obesity (DIO). |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ | |