| 耗竭性运动对大鼠心肌线粒体内膜流动性和复合体I的影响 |
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| 引用本文： | 张勇,张丰德.耗竭性运动对大鼠心肌线粒体内膜流动性和复合体I的影响[J].生物化学与生物物理学报,1995,27(3):337-340. |
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| 作者姓名： | 张勇 张丰德 |
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| 作者单位： | 天津体育学院运动医学研究所，南开大学生物系，北京体育大学 |
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| 摘 要： | 耗竭性运动对大鼠心肌线粒体内膜流动性和复合体Ｉ的影响张勇，李静先，陈家琦（天津体育学院运动医学研究所，３００３８１）张丰德（南开大学生物系，天津３０００７１）关键词心肌线粒体内膜，流动性，复合体Ｉ，过氧化脂质，耗竭运动有关运动对线粒体膜影响的研究表明...
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| 关 键 词： | 心肌 线粒体内膜 流动性 复合体I 耗竭运动 |
Influence of Exhaustive Exercise on Fluidity and Complex I of Heart Inner-mitochondrial Membranes in Rats |
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| ZHANG Yong,LI Jing-Xian, CHEN Jia-Qi and ZHANG Feng-De.Influence of Exhaustive Exercise on Fluidity and Complex I of Heart Inner-mitochondrial Membranes in Rats[J].Acta Biochimica et Biophysica Sinica,1995,27(3):337-340. |
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| Authors: | ZHANG Yong LI Jing-Xian CHEN Jia-Qi and ZHANG Feng-De |
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| Abstract: | Rats running with incremental intensity fo exhaustion were used as a model to investigate the influence of exhaustive exercise on heart inner-mitochondrial membranes(IMM). It was found that, in exhausted rats, the mioroviscosity of IMM increased by 74.4%(meaning a decrease of fluidity), the activity of NADHCoQ rednotase in the respiratory chain declined by 38.4%and the lipid peroxidation metabolite, malondialdehyde (MDA) increased by 39.4%in mitchondria. The result suggested that the exercise-induced increase of lipoperoxide may be responsible for changes of membranous molecular dynamics and function of complex I. |
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| Keywords: | Heart inner-mitochondrial membraneas Membrane fluidity Oomplex I Lipid peroxides Exhaustive exercise |
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