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Nystatin and killer toxin sensitivity of free and immobilizedSaccharomyces cerevisiae
Authors:V Jirk?
Institution:(1) Department of Fermentation Chemistry and Bioengineering, Institute of Chemical Technology, 166 28 Prague 6, Czechoslovakia
Abstract:The inhibitory effect of nystatin and killer toxin on the growth of free and covalently-immobilizedSaccharomyces cerevisiae cells was studied. The resistance of immobilized cells to both agents was accompanied by increased amounts of phospholipids and sterols. The possible relationship between these changes in the membrane composition and the transduction of a signal across the cytoplasmic membrane is discussed.
Keywords:Covalent linkage  immobilization  killer toxin  nystatin  Phospholipids  Signal transduction  sterols
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