Bacteriological tests as an aid in the management of dental caries in Iceland |
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| Authors: | Holbrook W P |
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| Institution: | (1) Department of Chemistry of Natural and Microbial Products, National Research Centre, Dokki, Cairo, Egypt |
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| Abstract: | The activities of three natural coumarins, xanthotoxin and bergapten (fromAmmi majus, Umbelliferae) and psoralene (fromFicus cycomorus, Moraceae), were tested against mycelial growth and aflatoxin production of a toxigenic strain ofAspergillus flavus grown in a rice/corn steep liquor medium. Two other natural chromones, khellin and visnagin (fromAmmi visnaga) were also compared. Complete inhibition of aflatoxin release occurred with either xanthotoxin or khellin at 5 mM. The other three compounds also at 5 mM reduced aflatoxin to 12 to 16% of its original concentration. The mould growth was only slightly inhibited by all the compounds used. |
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| Keywords: | Inhibition Aspergillus flavus aflatoxin coumarins chromones |
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