| 原核基因组的进化方向和癌／正常细胞的熵产生 |
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| 引用本文： | 罗辽复.原核基因组的进化方向和癌／正常细胞的熵产生[J].生物信息学,2014,12(1):1-4. |
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| 作者姓名： | 罗辽复 |
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| 作者单位： | 内蒙古大学物理学院,呼和浩特010021 |
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| 基金项目： | 国家自然科学基金项目(0,0);内蒙古自治区科学技术特别贡献奖励基金(2008)。 |
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| 摘 要： | 本文评述了理论生物学的两个基础实验。一是用离子束辐照加速大肠杆菌进化的方法研究原核基因组的进化方向,证明进化中的缺失偏好性和编码信息量扩增律不矛盾。二是提出用导热法测量细胞的熵产生,比较研究了癌细胞和正常细胞的熵产生和外加电场的关系,证明在一定强度的电场作用下正常细胞的熵产生可以明显超过癌细胞,从而实现改变两类细胞间熵流方向的目的。
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| 关 键 词： | 进化方向 原核基因组 细胞熵产生 电场 |
| 收稿时间： | 2013/9/28 0:00:00 |
Direction of prokaryotic genome evolution and entropy production of cancerous/normal cells |
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| LUO Liaofu.Direction of prokaryotic genome evolution and entropy production of cancerous/normal cells[J].China Journal of Bioinformation,2014,12(1):1-4. |
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| Authors: | LUO Liaofu |
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| Institution: | Department of Physics, Inner Mongolia University, Hohhot 010021, China |
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| Abstract: | Two experiments in theoretical biology were reviewed. One is on the direction of prokaryotic genome evolution studied by multiple ion irradiations on E coli to accelerate the evolution. It has proved that the deletion bias is not conflict with the law of the growing of coding information quantity. Another is a comparative study on the entropy production between cancerous and normal cells. Through the measurement of thermal conduction of cells under electric field the relationship between entropy production and field strength is obtained. It has proved that the field-induced entropy production in normal cells exceeds that in cancerous so that the direction of entropy flow between two kinds of cells can be reversed. |
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| Keywords: | Evolutionary direction Prokaryotic genome Cell entropy production Electric field |
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