| 家蚕浓核病毒中国(镇江)株结构蛋白的生物信息学比较分析 |
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| 引用本文： | 裘智勇,许光志,郭锡杰.家蚕浓核病毒中国(镇江)株结构蛋白的生物信息学比较分析[J].生物信息学,2007,5(2):58-61,66. |
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| 作者姓名： | 裘智勇 许光志 郭锡杰 |
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| 作者单位： | 1. 中国农业科学院蚕业研究所,江苏,镇江,212018;江苏科技大学,江苏,镇江,212018
2. 中国农业科学院蚕业研究所,江苏,镇江,212018 |
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| 基金项目： | 国家重点基础研究发展计划(973计划) |
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| 摘 要： | 运用生物信息学方法将家蚕浓核病毒中国(镇江)株的结构蛋白与其它类型家蚕浓核病毒的结构蛋白在理化特性、结构、功能等方面进行了比较分析。结果表明:家蚕浓核病毒结构蛋白是一类稳定的亲水性蛋白,BmDNV-ZJ与BmDNV-2的结构蛋白性质可能比较类似,而BmDNV-ZJ和BmDNV-1结构蛋白序列的理化性参数、序列内部重复片断以及折叠区域差异较大,表明这两种浓核病毒结构蛋白在性状、结构、功能上有较大差异。而BmDNV-ZJ和BmDNV-1结构蛋白序列中有3个不同的LCR功能区域。分子进化聚类分析可得到四大类浓核病毒结构蛋白。
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| 关 键 词： | 家蚕 浓核病毒 结构蛋白 生物信息学 |
| 文章编号： | 1672-5565（2007）-02-58-05 |
| 修稿时间： | 2006-05-262006-06-26 |
Comparative analysis of structural proteins of Bombyx mori densovirus (Zhenjiang Isolate)by using method of bioinformatics |
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| Qiu Zhiyong,Xu Guang zhi,Guo Xijie.Comparative analysis of structural proteins of Bombyx mori densovirus (Zhenjiang Isolate)by using method of bioinformatics[J].China Journal of Bioinformation,2007,5(2):58-61,66. |
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| Authors: | Qiu Zhiyong Xu Guang zhi Guo Xijie |
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| Institution: | Sericultural Research Institute, Chinese Academy of Agricultural Sciences, zhenjiang jiangsu 212018;Jiangsu Univerisity of Science and Technology , Zhenjiang 212018, Jiangsu, China |
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| Abstract: | The physic-chemical parameters,structure and function of structural proteins of several Bombyx mori densoviruses(BmDNVs),in- cluding BmDNVs Zhenjiang Isolate(BmDNV-ZJ)were comparatively analyzed by using the method of bioinformatics.The results showed that the structural proteins of BmDNVs were stable and hydrophilic.The structural protein of BmDNV-ZJ was similar with that d BmDNV-2 on properties,but different from BmDNV-1 on amino acid sequence properties such as physic-chemical parameters,internal sequence repeats and fold regions.There were three LCRs in the amino acid sequence of structural protein of BmDNV-25,and BmDNV-1 respectively.Four groups of densovirus structural proteins were got by molecalar evdutionary clustering analysis. |
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| Keywords: | bombyx mori Densovirus Structural Protein Bioinformatics |
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