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Toxoplasma gondii Mei2序列的电子延伸与分析
引用本文:黄云鹏,夏晓峰,柯崇榕,黄钦耿,江贤章,田宝玉,黄建忠.Toxoplasma gondii Mei2序列的电子延伸与分析[J].生物信息学,2008,6(3):102-105.
作者姓名:黄云鹏  夏晓峰  柯崇榕  黄钦耿  江贤章  田宝玉  黄建忠
作者单位:福建师范大学工业微生物教育部工程研究中心,福州,350108
摘    要:Mei2是调控细胞分裂过程的重要蛋白,利用电子延伸技术对Toxoplasma gondii EST数据库中的Mei2同源的ESTs进行了电子延伸,得到3836bp的Mei2同源电子延伸物,利用ORF Finder预测的相应的编码物为496个氨基酸的Mei2-predict protein,对该蛋白质的理化性质及结构进行了相关的预测与分析,结果显示T.gondii来源的Mei2-predict protein含有一个RBD结构域。系统发育分析表明Mei2-predict protein与Plasmodium来源的Mei2亲源关系最近。

关 键 词:电子延伸  Mei2  序列分析  系统发育分析

Electronic-extention and analysis of Mei2 in Toxoplasma gondii
HUANG Yun-peng,XIA Xiao-feng,KE Chong-rong,HUANG QIN-geng,Jing XIAN-Zhang,TIAN Bao-Yu,HUANG Jian-Zhong.Electronic-extention and analysis of Mei2 in Toxoplasma gondii[J].China Journal of Bioinformation,2008,6(3):102-105.
Authors:HUANG Yun-peng  XIA Xiao-feng  KE Chong-rong  HUANG QIN-geng  Jing XIAN-Zhang  TIAN Bao-Yu  HUANG Jian-Zhong
Institution:HUANG Yun - peng, XIA Xiao - feng, KE Chong - tong, HUANG QIN - geng, Jing XIAN - Zhang, TIAN Bao - Yu, HUANG Jian - Zhong ( Engineering Research Center of Industrial Microbiology, Ministry of Education, Fujian Normal University, FuZhou 350108, China)
Abstract:Mei2 is an important protein which acts as a regulator involved in meiosis process, we use the electronic- extenfion technology to extend the ESTs from Toxoplasma gondii EST database which homologous with Mei2. And we obtain 3836bp length eontig, it was predicted as encoding a 496 - amino acid length protein- "Mei2- predict protein". Then the bioinformatical prediction and analysis of protein structure are processed,the study showed that an RBD domain are contained in Mei2- predict protein. The following phylogenefic analysis of Mei2 - predict protein in our study showed that the Mei2- predict protein from T. gondii is similar to the Mei2 protein which was identified from Plasmodium.
Keywords:Mei2
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