| 氢化酶结构研究进展 |
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| 引用本文： | 杜明,任南琪,张璐,许继飞,邱颉.氢化酶结构研究进展[J].生物信息学,2009,7(4):323-325. |
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| 作者姓名： | 杜明 任南琪 张璐 许继飞 邱颉 |
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| 作者单位： | 1. 哈尔滨工业大学,市政环境工程学院,哈尔滨,150090;哈尔滨工业大学,食品科学与工程学院,哈尔滨,150090
2. 哈尔滨工业大学,市政环境工程学院,哈尔滨,150090 |
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| 基金项目： | 中国博士后科学基金，黑龙江省博士后基金 |
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| 摘 要： | 氢化酶是微生物代谢产氢过程中的关键酶，也是目前生物制氢领域的研究热点。本文综述了厌氧发酵产氢微生物中氢化酶的分类及特点，以及Ni—Fe]、Fe—Fe]和Fe—Scluster—free]三种氢化酶晶体结构和活性中心结构；阐述了多种微生物来源的氢化酶结构的研究进展，对几种典型氢化酶的结构及活性中心进行了对比分析，并根据当前研究热点，对氢化酶的研究方向进行了展望。本文阐述的内容信息量丰富且具有一定的实用性，对于氢化酶相关领域研究具有重要的意义。
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| 关 键 词： | 氢化酶 晶体结构 厌氧菌 进展 |
Review on Structure of Hydrogenase |
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| DU Ming,REN Nan-qi,ZHANG Lu,XU Ji-fei,QIU Jie.Review on Structure of Hydrogenase[J].China Journal of Bioinformation,2009,7(4):323-325. |
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| Authors: | DU Ming REN Nan-qi ZHANG Lu XU Ji-fei QIU Jie |
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| Institution: | 1. Sctwol of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China ; 2. College of Food Science and Engineering, Harbin Institute of Technology, Harbin 150090, China) |
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| Abstract: | Hydrogenase is the key enzyme and plays an important role in the process of biohydrogen production, which is an interesting topic in this research field. In the paper, the classification of hydrogenase was described. According to lots of research results, the recent reports of crystal structure and active site structure of the three kinds of hydrogenases, Ni-Fe],Fe-Fe] and Fe-S cluster-free], were quoted and contrasted. Moreover, some new approach and direction for hydrogenases were indicated. This review is informative and useful. The overall presentation is good for the relative studies on hydrogenases. |
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| Keywords: | Hydrogenase Crystal Structure Anaerobe bacteria Advance |
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