硫酸镁微量气泵吸入治疗毛细支气管炎患儿的疗效及对肺功能的影响

目的:探讨硫酸镁微量气泵吸入治疗毛细支气管炎患儿的疗效及对肺功能的影响。方法:选择2012年1月-2014年8月我院收治的毛细支气管炎患儿120例,随机分为研究组和对照组各60例。两组均给予吸氧、吸痰、镇静、止咳、抗感染和支气管扩张剂治疗,研究组再加用25%硫酸镁溶液0.1~0.2ml/(kg.次)气泵吸入治疗,比较两组临床疗效及患儿肺功能变化。结果:研究组总有效率为98.3%,显著高于对照组的88.3%(P0.05);研究组患儿咳嗽、气促、喘息、肺部哮鸣音/啰音消失时间及住院时间显著短于对照组(P0.05);治疗后两组患儿潮气量(VT)、达峰时间比(t PTEF/t E)和v PTEF/v E均明显升高,吸呼比(Ti/Te)明显降低(P0.05),研究组VT、t PTEF/t E和v PTEF/v E显著高于对照组,Ti/Te显著低于对照组(P0.05)。结论:硫酸镁微量气泵吸入治疗小儿毛细支气管炎可以改善患儿喘憋、气促、呼吸困难等症状以及肺功能,临床效果较好。

Curative Effect of Magnesium Sulfate Micro Pump Inhalation in the Treatment of Children With Bronchiolitis and Its Effect on Pulmonary Function

Objective:To investigate the effect of magnesium sulfate micro pump inhalation in the treatment of children with bronchiolitis and its effect on pulmonary function.Methods:Selected 120 cases of children with bronchiolitis who were treated in our hospital from January 2012 to August 2014, which were randomly divided into study group and control group with 60 cases in each group. The two groups were given oxygen inhalation, cough, sputum suction, sedation, anti infection and bronchodilator treatment, the study group were added with 25%magnesiumsulfate solution 0.1~0.2 mL/(kg) pump inhalation treatment, compared the clinical curative effect and the changes of pulmonary function between the two groups.Results:The total efficiency of the study group was 98.3%, significantly higher than that 88.3%in the control group (P<0.05). Disappear time of children with cough, shortness of breath, wheezing, pulmonary wheezing/rales and the hospitalization time in the study group was significantly shorter than that of the control group(P<0.05). The tidal volume (VT), time to peak ratio (tPTEF/tE) and (vPTEF/vE) significantly increased and respiratory ratio (Ti/Te) decreased significantly after treatment (P<0.05), the VT, tPTEF/tE and vPTEF/vE of study group were significantly higher than that of the control group, Ti/Te was significantly lower than that of the control group(P<0.05).Conclusion:Magnesiumsulfate micro pump inhalation in the treatment of children with bronchiolitis can improve the symptoms such as wheezing, shortness of breath, dyspnea, improve lung function, and the clinical effect is good.