胚胎型大脑后动脉与脑白质病之间的关系

目的:探讨胚胎型大脑后动脉(Fetal origin of the posterior cerebral artery,FTP)与脑白质病之间的关系。方法:收集2013年1月~2014年6月在我院住院患者共485例,所有患者均行头颅磁共振平扫及血管成像,观察脑白质病变、急性脑梗死及FTP存在与否,并分为观察组(脑白质病组)和对照组(无脑白质病组),比较FTP的发生率。结果:观察组和对照组分别为232例和253例,观察组共发现53例FTP患者(左侧、右侧、双侧FTP分别为15例、19例、19例),FTP总发生率为22.8%,左侧、右侧、双侧FTP发生率分别为6.5%、8.2%、8.2%;对照组98例FTP患者(左侧、右侧、双侧FTP分别为26例、44例、28例),FTP总发生率为38.7%,左侧、右侧、双侧FTP发生率分别为10.3%、17.4%、11.1%,观察组FTP总发生率及右侧FTP发生率明显低于对照组(P0.001和P0.01)。232例观察组中急性脑梗死患者共156例,无急性脑梗死患者76例,其中急性脑梗死组有28例FTP患者(左侧、右侧、双侧FTP分别为7例、15例、6例),FTP总发生率及左侧、右侧、双侧FTP发生率分别为17.9%、4.5%、9.6%、3.8%;而无急性脑梗死的患者中,有24例FTP患者(左侧、右侧、双侧FTP分别为8例、4例、12例),FTP总发生率及左侧、右侧、双侧FTP发生率分别为31.6%、10.5%、5.3%、15.8%,观察组FTP总发生率及双侧FTP发生率明显低于对照组(P0.05和P0.01)。结论:FTP的存在可能一定程度上降低脑白质病甚至脑梗死的发生。

Relationship between Fetal Origin of the Posterior Cerebral Artery and Cerebral White Matter Lesion

Objective:To explore the relationship between fetal origin of the posterior cerebral artery (FTP) and cerebral white matter lesion.Methods:A total of 485 hospitalized patients were recruited in our hospital from 2014 January to 2015 June. All patients underwent brain magnetic resonance imaging scan and angiography. Cerebral white matter lesion, acute cerebral infarction and FTP were observed. All patients were randomly divided into observation group with white matter lesion and control group without white matter lesion. The incidence of FTP was compared.Results:The observation group and control group included 232 and 253 cases, respectively. Fifty-three patients with FTP were detected in observation group (15 cases, 19 cases, 19 cases with left, right and bilateral FTP, respectively). The incidence of total FTP was 22.8 %. The incidence of left, right and bilateral FTP was 6.5 %, 8.2%and 8.2 %, respectively. In contrast, there were 98 FTP patients in control group (26 cases, 44 cases, 28 cases with left, right and bilateral FTP, respectively). The incidence of total FTP was 38.7 %. The incidence of left, right and bilateral FTP was 10.3 %, 17.4 % and 11.1 %, respectively. The incidence of total and right FTP in observation group was much lower than that in control group (P<0.001 and P<0.01). In our results, there were 156 and 76 cases with and without acute cerebral infarction, respectively, in observation group with 232 patients. Twenty-eight FTP cases were found in patients with cerebral infarction (7 cases, 15 cases, 6 cases with left, right and bilateral FTP, respectively). The incidence of total, left, right and bilateral FTP was 17.9 %, 4.5 %, 9.6 %and 3.8 %, respectively. There were 24 FTP cases without cerebral infarction (8 cases, 4 cases, 12 cases with left, right and bilateral FTP, respectively). The incidence of total, left, right and bilateral FTP was 31.6 %, 10.5 %, 5.3 % and 15.8 %. There was significant reduction in the incidence of total and bilateral FTP in observation group compared with control group (P<0.05 and P<0.01).Conclusion:FTP might reduce the occurrence of white matter lesion and even cerebral infarction.