利拉鲁肽治疗2型糖尿病的研究进展

利拉鲁肽是一种胰高糖素样肽-1(GLP-1)类似物,作为一种新型的2型糖尿病治疗药物,具有降低体质量、改善胰岛β细胞功能、降低收缩压,减少低血糖发生率的作用。本文通过对近期国内外文献中关于利拉鲁肽研究进展的归纳和分析,从其药理作用研究、动物实验研究、临床研究、安全性和耐受性等方面进行阐述,为今后的研究提供参考和依据。

Progress on the Application of Liraglutide Treatment of Diabetes

Liraglutide is a glucagon-like peptide -1 (GLP-1) analogue, as a new type 2 diabetes drug, with lower body mass, improve islet beta-cell function, reduced systolic blood pressure reduce the incidence of hypoglycemia role. Based on the recent literature are summarized and analyzed with regard to the progress of liraglutide, its pharmacological effects, animal studies, clinical studies, the safety and tolerability aspects elaborated to provide a reference for future research and basis.