经尿道2微米激光切除术与电切术治疗浅表性膀胱癌的疗效观察

目的:比较经尿道2微米激光切除术与电切术治疗浅表性膀胱癌的临床疗效。方法:按照随机数字表法将2014年1月-2015年1月我院收治的浅表性膀胱癌患者分为两组,观察组(61例)行经尿道2微米激光切除手术,对照组(46例)行电切术,比较两组的手术效果、治疗前后的炎症因子水平及并发症。结果:观察组手术时间、导尿管留置时间、住院时间及术中出血量少于对照组,差异有统计学意义(P0.05)。治疗后两组患者IL-6、IL-10以及TNF-α水平均较治疗前升高,但是观察组治疗后的IL-6及TNF-α水平低于对照组,IL-10水平高于对照组,差异有统计学意义(P0.05)。两组患者术后均发生不同程度的并发症,其中观察组膀胱穿孔、闭孔神经反射的发生率为3.28%、1.64%,分别低于对照组的17.39%、13.04%,差异有统计学意义(P0.05)。结论:浅表性膀胱癌采用经尿道2微米激光切除术治疗具有明显的临床手术效果,减少术后并发症,同时对患者炎症因子的影响较小,临床有重要的参考价值。

Comparison of Transurethral 2 Micron Laser Resection and Electrocision for Superficial Bladder Cancer

Objective:To compare the clinical effect of transurethral 2 micron laser resection and electrocision for superficial bladder cancer.Methods:A total of 107 patients with superficial bladder cancer, who were admitted to First Affiliated Hospital of Chongqing Third Military Medical University from January 2014 to January 2015, were randomly divided into observation group(n=61) and control group (n=46). The observation group underwent transurethral 2 micron laser resection, while the control group underwent electrocision. The operation effect, inflammation factors levels before and after operation, and the complications were compared.Results:A total of 107 patients with superficial bladder cancer, who were admitted to First Affiliated Hospital of Chongqing Third Military Medical University from January 2014 to January 2015, were randomly divided into observation group(n=61) and control group (n=46). The observation group underwent transurethral 2 micron laser resection, while the control group underwent electrocision. The operation effect, inflammation factors levels before and after operation, and the complications were compared.Conclusion:Transurethral 2 micron laser resection has remarkable operation effect in the treatment of patients with superficial bladder cancer, with reducing the postoperative complication and slightly influencing the inflammatory factors level, which has an important reference value in the clinical field.