腹腔镜下卵巢囊肿剥除术前后AMH与bFSH水平的变化与临床价值

目的:对腹腔镜下行卵巢囊肿剥除术患者在手术前和手术后的AMH(anti-mullerian hormone,抗苗勒氏管激素)和bFSH(basic Follicle-stimulating hormone,基础促卵泡刺激素)含量进行测定,分析其临床意义和价值。方法:将2012年1月~2014年1月期间来我院妇产科就诊的34例卵巢巧克力囊肿患者作为研究组,上述患者经相关检查均身体状况符合腹腔镜手术的要求,并选取同期36例非巧囊患者作为对照组,2组患者均实施腹腔镜下卵巢囊肿剥离术进行治疗,并分别在手术前和手术完毕时对患者的AMH和bFSH水平进行测定。结果:研究组与对照组患者在手术完毕后AMH含量(2.02±2.11,2.77±1.62)ng/m L]同手术前(2.88±2.30,3.08±1.81)ng/m L]对比具有明显降低,具有统计学差异,(P0.05),研究组患者降低水平更为显著;研究组手术完毕b FSH含量(6.83±1.80)μU/m L明显高于术前(6.29±2.11)μU/m L,具有统计学差异(P0.05),而对照组患者术后血清bFSH含量同术前比较并未明显上升,无统计学差异(P0.05)。结论:行腹腔镜卵巢囊肿剥除术能够使患者的卵巢储备能力下降,测定AMH较b FSH能够更好的反应出卵巢手术后卵巢储备状况。

The Change of AMH and bFSH Level before and after Laparoscopic Ovarian Cystectomy and Clinical Value

Objective:To determine the level of AMH and bFSH of the patients that implemented laparoscopic ovarian cystectomy before and after Operation, to analyze its clinical significance and value.Methods:34 cases of ovarian chocolate cyst patients in 2012 January ~2014 January in our hospital obstetrics and gynecology clinic as the study group, the patients by the relevant examination body condition conforms to the requirements of laparoscopic operation, and selected 36 cases of non chocolate cyst patients as control group, 2 group of patients underwent laparoscopic ovarian cystectomy for the treatment, and were in operation before and after operation of patients with AMH and bFSH level were measured.Results:The research group and control group patients in operation after the completion of the AMH content (2.02 ± 2.11, 2.77 ± 1.62) ng/mL] before contrast surgery (2.88 ± 2.30, 3.08 ± 1.81) ng/mL] has decreased significantly, and the difference is statistically significant (P < 0.05). Patients in study group were reduced levels is more significant; the study group operation completed bFSH content (6.83 ± 1.80) uU/mL was significantly higher than that before operation (6.29 ± 2.11) uU/mL, with significant difference (P < 0.05), while the control group of patients with postoperative bFSH concentration in serum with preoperative no increased significantly, no significant difference (P > 0.05).Conclusion:Laparoscopic ovarian cyst stripping can decrease the ovarian reserve capacity, and the AMH is better than bFSH, which can reflect the ovarian reserve after ovarian surgery.