射频消融改善阵发性和长期持续性心房颤动患者生活质量的研究

目的:比较射频消融对阵发性和长期持续性心房颤动(房颤)患者生活质量的改善。方法:纳入2011年5月至2016年8月接受射频消融治疗的阵发性房颤患者142例和长期持续性房颤61例。消融前和消融后12个月采用健康状况调查简表(SF-36)评估患者生活质量。结果:长期持续性房颤患者年龄及合并高血压和慢性心功能不全的比例高于阵发性房颤组。消融后12个月,两组患者心理健康(MCS)和生理健康(PCS)评分均显著提高(P0.01)。长期持续性房颤患者MCS和PCS的改善幅度显著高于阵发性房颤组(P0.01)。房颤未复发患者生活质量的提高幅度显著高于复发患者(P0.01)。结论:射频消融改善长期持续性房颤患者生活质量的幅度高于阵发性房颤,房颤复发将影响患者的生活质量。

Improvement in Quality of Life after Radiofrequency Ablation for Paroxysmal and Long-standing Persistent Atrial Fibrillation

ABSTRACT Objective: To compare the improvement in quality of life after radiofrequency ablation for paroxysmal and long-standing persistent atrial fibrillation (AF). Methods: 142 patients with paroxysmal AF and 61 patients with long-standing persistent AF who received radiofrequency ablation were enrolled between May 2011 and August 2016. Quality of life was evaluated using the 36-Item Short Form Health Survey (SF-36) at baseline and 12 months after the ablation. Results: Age and the percentages of hypertension and chronical heart failure were higher in patients with long-standing persistent AF than those with paroxysmal AF. At 12 months after the ablation, the mental (MCS) and physical component summary (PCS) scores were significantly increased in both groups compared with the scores at baseline (P<0.01). The improvements in MCS and PCS were higher in patients without recurrent AF than those with recurrent AF (P<0.01). Conclusion: The improvement in quality of life after radiofrequency ablation is superior in patients with long-standing persistent AF than in paroxysmal AF, and AF recurrence impairs quality of life.