二维斑点追踪技术对主动脉瓣狭窄左室纵向应变的评价研究

目的:探讨超声二维斑点追踪成像技术(2DSTI)评价主动脉瓣狭窄(AS)患者左室功能早期改变的临床价值。方法:选取我院自2012年4月至2012年12月左室射血分数(LVEF)正常的AS(中-重度)患者30例(AS组),正常对照组30例。获取心尖位左室长轴观、二腔观和四腔观各节段收缩期纵向峰值应变(SL),并计算左室基底段、中间段、心尖段SL平均值及左室整体纵向应变值(GLS)。结果:AS组与对照组的左室射血分数差异无统计学意义(P0.05),AS组与对照组的主动脉瓣瓣口面积及平均压差具有统计学意义(P0.05);AS组患者整体、基底段、中间段、心尖段的GLS均低于对照组(P0.05)。结论:超声二维斑点追踪成像技术能够评价主动脉瓣狭窄左室心肌收缩功能的早期异常改变。

Application of Two-dimensional Speckle Tracking Imaging in the Evaluation of Aortic Stenosis

ABSTRACT Objective:To investigate the value of two-dimensional speckle tracking imaging (2D STI) in assessing the left ventricular systolic function of aortic stenosis (AS).Methods: 2D STI was applied in 30 patients with preserved left ventricular ejection fraction (LVEF) of aortic stenosis( AS group) in our hospital from April 2012 to December 2012, 30 normal cases were used as controls. Each segment of LS of the apical left ventricular long axis view, two chamber view and four chamber view were collected.The GLS as well as SL average value of the left ventricular basal segment, the middle section and apogee were calculated.Results: There was no significant difference in LVEF between the two groups (P > 0.05), but there was statistical difference in Aortic valve area and average pressure (P < 0.05). The overall, basal section, the middle section, apical GLS of AS groups were lower than those of the control group(P < 0.05). Conclusion:2D STI can provide a sensitive method for the evaluation of LV systolic function changes in AS.