运动对细胞凋亡的影响

细胞凋亡是一种由基因控制的细胞自主性死亡过程,其性质为生理性细胞死亡。细胞凋亡的研究已成为生物医学领域中最热门的课题之一。运动可以诱导细胞凋亡,细胞凋亡发生的比率和程度与运动形式、运动强度和运动持续时间有关,其机制可能主要包括以下方面:影响凋亡相关基因、自由基的介导使氧化与抗氧化系统失衡,损伤线粒体的结构和功能以及机械损伤。为此就运动对细胞凋亡影响的一些新的研究进展进行了综述。

Effects of Exercise on Apoptosis

Apoptosis is an initiative cell death process that is controlled by gene and it is a kind of physiological cell death. Apoptosis has become one of study warm points and forward positions in biology and medicine. Apoptosis of cell was induced by exercise and the incidence and level of apoptosis related to the mode, intensity and sustained time of exercise. The main possible mechanisms consisted of the followings: factors of apoptosis-related gene, free radical inducing resulted un-equilibrium between oxidant and antioxidant system, mitochondrial structure and function injury, as well as mechanical injury. This paper reviewed some new progress about effects of exercise on apoptosis.