兰州地区健康体检者血脂水平分析

目的:通过检测兰州地区健康体检者空腹血脂水平了解本地区人群血脂水平现状及血脂异常情况,建立本地区血脂参考值。方法:采用全自动生化分析仪检测兰州市2328名健康体检者,血清胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)。比较不同年龄、性别血脂水平差异。结果:本地区2328名被检者,女性TC平均(4.54±0.94)mmol/L,TG中位数1.24mmol/L、HDL-C平均(1.34±0.26)mmol/L、LDL-C平均(2.61±0.76)mmol/L;男性TC平均(4.52±0.84)mmol/L、TG中位数1.56mmol/L mmol/L、HDL-C平均(1.20±0.23)mmol/L LDL-C平均(2.76±0.72)mmol/L,血脂水平随年龄增加逐渐升高(P<0.05)。血脂参考范围为女性TC:2.70~6.38 mmol/L、TG:0.52~3.66 mmol/L、HDL-C:0.83~1.85 mmol/L、LDL-C:1.12~4.10 mmol/L男性:TG:2.87~6.17 mmol/L、0.65~4.00 mmol/L、0.75~1.65 mmol/L、1.35~4.17 mmol/L。男性高TC、高TG、低HDL-C和高LDL-C患病率为18.2%、42.8%、19.6%和28%,女性高TC、高TG、低HDL和高LDL的患病率分别为22.1%、25.5%、2.7%和23.5%。结论:兰州地区血脂水平随年龄、性别、地区不同存在较大差异,临床上不能采用统一标准衡量,而应根据本地区建立的参考值诊断高脂血症。积极控制血脂水平、降低高脂血症患病率预防心脑血管疾病发生。

The Analysis of Serum Lipids of Healthy Adults in Lanzhou

Objective: To evaluate the status of the morbidity of serum lipids and establish reference value through the detection of healthy people in Lanzhou.Methods: The serum total cholesterol(TC),triglyceride(TG),high density lipoprotein cholesterol(HDL-C) and low density lipoprotein(LDL-C) were detected by automatic biochemical analyzer in 2328 healthy adults in Lanzhou.Analysis blood lipid level distribution in different age and gender.Results: The average levels of TC,TG HDL-C andLDL-C.were(4.54± 0.94) mmol / L,1.24 mmol /L,(1.34± 0.26) mmol / L and(2.61± 0.76) in female,(4.52±0.84) mmol /L,1.56 mmol /L,(1.20±0.23) mmol /L,(2.76±0.72) mmol /L in male.TC,TG,LDL gradually increased with age(P <0.05).Reference range of blood TC,TG,HDL-C and LDL-C were(2.70-6.38) mmol / L,(0.52-3.66) mmol / L,(0.83-1.85) mmol / L and(1.12-4.10) mmol / L in female and(2.87-6.17) mmol / L,(0.65-4.00) mmol / L,(0.75-1.65) mmol / L and(1.35-4.17) mmol / L in male.The proportion of the four dyslipidemia were 18.2%,42.8%,19.6%,28% in men and 22.1%,25.5%,7.2%,23.5% in women.Conclusion: The distribution in different age,gender and region were obviously.It must be established the reference value in this region rather than the uniform standards to diagnose hyperlipidemia in order to reduce the prevalence rate of hyperlipidemia and prevent cardiovascular diseases.