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肿瘤标志物在卵巢恶性肿瘤早期误诊预防中的价值
引用本文:王志恒刘晓艳,张彬徐文彬唐慧琳.肿瘤标志物在卵巢恶性肿瘤早期误诊预防中的价值[J].现代生物医学进展,2012,12(12):2302-2304.
作者姓名:王志恒刘晓艳  张彬徐文彬唐慧琳
作者单位:复旦大学附属妇产科医院检验科 上海200011
摘    要:目的:探讨糖类抗原CA125、CEA与CA199联合检测对卵巢癌有一定的鉴别诊断价值。方法:应用化学发光免疫法对126例经病理查证实的卵巢癌患者(试验组)、104例良性肿瘤患者(对照组)进行血清CA125、CEA与CA199检测。结果:试验组血清检测结果和阳性率均明显高于对照组(P<0.01),联合检测阳性率高于单项检测(P<0.01)。结论:应用检验医学进行CA125、CEA与CA199联合检测对卵巢癌有一定的鉴别诊断价值。可降低误诊率。

关 键 词:卵巢癌  早期  糖类抗原联合检测  鉴别诊断

Value of Tumor Markers in Ovarian Cancer is Misdiagnosed Prevention
WANG Zhi-heng,LIU Xiao-yan,ZHANG Bin,XU Weng-bin,TANG Hui-lin.Value of Tumor Markers in Ovarian Cancer is Misdiagnosed Prevention[J].Progress in Modern Biomedicine,2012,12(12):2302-2304.
Authors:WANG Zhi-heng  LIU Xiao-yan  ZHANG Bin  XU Weng-bin  TANG Hui-lin
Institution:(Fudan University affiliated obstetrics and gynecology hospital laboratory 200011,China)
Abstract:Objective: To investigate the value of combination detection of carbohydrate antigen CA125,CEA and CA199 for differential diagnosis on patients with ovarian cancer.Methods: Chemiluminescence immunoassay was used to detect serum CA125,CEA and CA199 levels of the 126 patients who were confirmed with ovarian cancer by pathology investigation(experimental group) and 104 patients with benign tumors(control group).Results: The serum test results and the positive rate of the experimental group was significantly higher than that of control group(P <0.01).Combination detection showed a higher positive rate(P <0.01) than the individual detection.Conclusion: Combination detection of CA125,CEA and CA199 had significance in the differential diagnosis of ovarian cancer.It can reduce the rate of misdiagnosis.
Keywords:Ovarian cancer  Early stage  Carbohydrate antigen joint detection  Differential diagnosis
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