乳酸依沙吖啶联合子宫颈扩张单球囊对瘢痕子宫中期妊娠引产的应用效果

目的:研究乳酸依沙吖啶联合子宫颈扩张单球囊对瘢痕子宫中期妊娠引产的应用效果。方法:选择2014年4月~2016年12月在我院进行诊治的由于社会因素或者医学因素自愿要求终止妊娠并无任何引产禁忌证的110例健康中期妊娠(孕周14~27周)孕妇为研究对象,随机分为观察组与对照组,每组各55例。对照组采用常规方案进行引产,即口服米非司酮150 mg,并在B超引导下经腹壁行羊膜腔内注射100 mg乳酸依沙吖啶;观察组采用乳酸依沙吖啶联合子宫颈扩张单球囊进行引产。比较两组孕妇的引产成功率、产程时间、宫缩发动时间、胎儿娩出时间、产后2 h出血量、住院时间、引产并发症的发生情况以及多次剖宫产患者的引产成功率。结果:观察组孕妇的引产成功率为96.36%(53/55),明显高于对照组83.64%(46/55)](P0.05),且观察组的产程时间、宫缩发动时间、产后2 h出血量以及住院时间均明显低于对照组(P0.05)。对照组多次剖宫产孕妇引产成功率为33.33%(2/6),观察组多次剖宫产孕妇引产成功率为100.00%(7/7),观察组明显高于对照组(P0.05)。对照组发生宫颈裂伤1例,会阴裂伤1例,两组孕妇均未出现羊水栓塞、子宫破裂以及感染等并发症。结论:乳酸依沙吖啶联合子宫颈扩张单球囊用于瘢痕子宫中期妊娠引产的应用效果明显优于口服米非司酮并在B超引导下经腹壁行羊膜腔内注射乳酸依沙吖啶,且安全性高。

Application Effect of Ethacridine Combined with Cervical Dilatation Single Balloon on Scar Uterine Mid Pregnancy Induced Labor

ABSTRACT Objective: To investigate the clinical effect of ethacridine combined with cervical dilatation single balloon on the scar uterine mid pregnancy induced labor. Methods: 110 cases of pregnant women (gestational age 14 ~ 27 weeks) who were treated in our hospital from April 2014 to December 2016 due to social factors or medical factors of voluntary termination of pregnancy and without any contraindication labor were selected and randomly divided into two groups, 55 cases in each group. The control group was given conventional scheme of induction, including 150 mg mifepristone and ultrasound guided transabdominal amniotic cavity injection of ethacridine lactate 100 mg; the observation group was treated with ethacridine combined with cervical dilatation of single balloon induc- tion. The success rate of induction of labor, labor time, the time of uterine contraction, fetal childbirth time, 2 h postpartum bleeding, hos- pitalization time, abortion complications and multiple cesarean section patients with success rate were compared between two groups. Results: The success rate of induction of labor in observation group was 96.36% (53/55), which was significantly higher than that of the control group83.64 % (46/55)](P<0.05); the labor time, time of uterine contraction, 2 h postpartum bleeding volume and hospitalization time of observation group were significantly lower than those of the control group (P<0.05). The successful induction rate of pregnant women with repeated cesarean section in control group was 33.33% (2/6), which was 100% in the observation group and was significantly higher than that of the control group(P<0.05). One cases of cervical laceration and perineal laceration occurred in the control group, and there was no complications such as amniotic fluid embolism, uterine rupture and infection in the two groups of pregnant women. Conclusion: Ethacridine combined with cervical dilatation of single balloon had better effect on uterine scar pregnancy induced labor with high safety.