氨氯地平联合美托洛尔治疗原发性高血压的临床疗效观察

目的：观察氨氯地平联合美托洛尔治疗高血压的临床效果及安全性。方法：对2012年4月至2012年11月期间在我科住院治疗的102例患者随机分成两组，对照组接受氨氯地平治疗，治疗组在对照组的基础上使用美托洛尔治疗，分析比较两组的疗效。结果：治疗组和对照组的血压以及心率较治疗前明显降低，差异有统计学意义（P〈0．01）；治疗组治疗后的舒张压与对照组治疗后的舒张压相比，差异有统计学意思（P〈0．01）；治疗组的总有效率高于对照组（P〈0．05）；治疗组的副反应低于对照组（P〈0．05）。结论：氨氯地平联合美托洛尔治疗高血压效果显著，优于单纯应用氨氯地平。

Clinical Observation of Amlodipine Combined with Metoprolol in Treating Essential Hypertension

Objective： To explore the clinical effect of amlodipine combined with metoprolol in treating essential hypertension. Methods： 102 patients who accepted treatment between April 2012 and Nov 2012 in our hospital were divided randomly into two groups. The control group was treated with amlodipine, and the treating group was treated with amlodipine plus metoprolol. The curative effect was compared between the groups. Results： After treatment, the blood pressure and heart rate declined obviously compared with that before treatment in two groups, and the difference was significantly statistical （P〈0.01）. The diastolic blood pressure after treatment decreased quicker in the treating group than that in the control group （P〈0.01）. The total effect rate was higher in treating group than that in control group, and the side effects was lower in treating group than that in control group （P〈0.01）. Conclusion： The amlodipine combined with metoprolol had better curative effect than amtodipine alone in treating hypertension.