帕金森病衣架样疼痛及治疗策略

目的:衣架样疼痛(coat-hanger ache,CHA)是帕金森病(Parkinson disease,PD)疼痛的一个少见类型,本文研究帕金森病合并衣架样疼痛的血压状况及治疗策略。方法:本文以15例伴有CHA的PD患者为研究对象,以不伴有CHA年龄、性别大致匹配的PD病人为对照,观察两组病人卧立位血压的变化及CHA组直立后出现疼痛的时间和评分,找到相应的治疗措施。结果:CHA组伴有体位性低血压(orthostatic hypotension,OH)的比例为80%,明显高于对照组(33%),站立后出现疼痛的时间为7.2±1.2,疼痛评分为3.5±2.1,给予改善OH的物理及药物治疗,大部分DHA病人有效。结论:PD病人伴有CHA可能与OH有关,改善血压状况后部分有效。

Coat-hanger Ache in Parkinson Disease and Treatment Strategy

Objective:Coat-hanger ache (CHA) is a rare type of pain in Parkinson disease (PD). The aim is to investigate the change of blood pressure in PD patients with CHA and the treatment strategy.Methods:15 PD patients with CHA compared with non-CHA PD group. All patients were given supine-standing blood pressure measure. Time of CHA appearance from standing up was calculated.Results:80% CHA group patients coupled with OH, obviously higher than non-CHA PD group. The time from standing to CHA appearance was 7.2± 1.2. Pain score was 3.5± 2.1. Most of CHA patients was relieved after physical and drug therapy of OH.Conclusion:PD patients coupled with CHA is probably related to OH. Improving OH state is effective for PD coupled with CHA.