| caveolin-1 mRNA在小鼠牙发育过程中的表达 |
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| 引用本文： | 杨林,何永红,沈永岱,刘磊,汤伟,郑晓辉,田卫东.caveolin-1 mRNA在小鼠牙发育过程中的表达[J].现代生物医学进展,2007,7(7):1028-1030. |
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| 作者姓名： | 杨林 何永红 沈永岱 刘磊 汤伟 郑晓辉 田卫东 |
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| 作者单位： | 四川大学华西口腔医学院颌面外科,四川,成都,610041 |
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| 摘 要： | 目的:检测caveolin-1基因mRNA在小鼠牙发育不同时期间充质细胞中的表达,初步探讨caveolin-1在小鼠牙胚发育过程中的作用。方法:以E9.5第一鳃弓间充质细胞及E16.5下颌第一磨牙牙胚细胞作为研究发育机制的模型,应用RT-PCR技术检测caveolin-1 mRNA的表达。结果:caveolin-1 mRNA在两种细胞中均有表达,其在牙胚细胞中的表达水平高于第一鳃弓间充质细胞。结论:caveolin-1可能在牙发育过程中发挥作用。
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| 关 键 词： | 间充质细胞 发育 |
| 文章编号： | 1673-6273（2007）07-1028-03 |
| 修稿时间： | 2007-04-212007-05-17 |
The Expression of Caveolin-1 mRNA in Tooth Development of Mouse |
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| YANG Lin, HE Yong-hong, SHEN Yong-dai, LIU Lei, TANG Wei, TIAN Wei-dong.The Expression of Caveolin-1 mRNA in Tooth Development of Mouse[J].Progress in Modern Biomedicine,2007,7(7):1028-1030. |
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| Authors: | YANG Lin HE Yong-hong SHEN Yong-dai LIU Lei TANG Wei TIAN Wei-dong |
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| Institution: | Department of Oral and Maxill of adal Surgery, West China College of Stomatology, Sichuan University, Chengdu 610041, China |
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| Abstract: | Objective:To study the expressidon of caveolin-1 mRNA in tooth development of mouse with different mes- enchymal cells.Methods:Total RNA was extracted from E9.5 ectoderm mesenchymal cells and E16.5 tooth germ mesenchymal cells of mouse and the gene mRNA was determined by using RT-PGR technique.Results:caveolin-1 mRNA was detected in both mesenchymal cells and its level in tooth germ mesenchymal cells is higer than that in ectoderm mesenchymal cells.Conclu- sion:caveolin-1 may play a important role in tooth development of mouse. |
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| Keywords: | caveolin-1 |
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