基于Web of Science的合成生物学文献计量分析

合成生物学是一个新兴的交叉学科,近年来得到了广泛关注。本文以1992-2012年期间Web of Science数据库收录的5012篇与合成生物学相关的论文为研究对象,进行年代分布、地域分布、机构分布、研究热点等方面的计量分析,以探究合成生物领域的研究实力分布、研究热点与发展动态。通过文献计量分析发现合成生物学领域近十年来发展迅猛,美国等发达国家占据主动。我国在该领域的论文产出数量可观,但学术影响力有待提高。研究的热点主要集中在基因调控网络构建、基因基因组合成、功能回路设计等方面。

Bibliometrics Analysis of Synthetic Biology Based on Web of Science

Synthetic biology is an emerging cross-discipline, which arouses great attention in recent years. Based on 5012 articles published during 1992~2012 in web of science citation database, the status of synthetic biology research was analyzed. The searching results were analyzed concerning the article numbers and the total citation by years, countries, and institutes, which helped to find out the distribution of research strength in the field of synthetic biology. In an effort to discover the research progress and focuses, the authors also analyzed the hot key words and hot papers. After bibliometrics analysis, the author found out that synthetic biology develops rapidly in recent ten years, mainly promoted by developed countries, such as the US. China has a large number of research papers in this field but the academic impact need to be improved. The research mainly focuses on construction of gene regulatory networks, gene synthesis and genome synthesis, genetic circuit, chassis organisms and minimal genome and so on.