| 嗜酸乳杆菌LB10.16及枯草芽孢杆菌BS7.29安全性评价 |
| |
| 引用本文： | 李军训,高洁,陈坤,张同存,杜连祥.嗜酸乳杆菌LB10.16及枯草芽孢杆菌BS7.29安全性评价[J].现代生物医学进展,2011,11(1):22-25. |
| |
| 作者姓名： | 李军训 高洁 陈坤 张同存 杜连祥 |
| |
| 作者单位： | 1. 天津科技大学工业微生物教育部重点实验室,天津,300222
2. 泰山学院生物科学系,山东,泰安,271000 |
| |
| 基金项目： | 国家高技术研究发展计划项目资助(863计划)(2008AA10Z336) |
| |
| 摘 要： | 目的:评价枯草芽孢杆菌BS7.29和嗜酸乳杆菌LB10.16的安全性,为其应用研究提供技术支持。方法:本文通过对小鼠灌服、急性攻毒、腹腔注射、小鼠最大耐受剂量、急性攻毒等试验方法进行枯草芽孢杆菌BS7.29和嗜酸乳杆菌LB10.16的安全性研究。结果:1×108cfu/kg.bw的LB10.16和5×108cfu/kg.bw的BS7.29能够明显提高肠道推动力,改善小鼠肠道蠕动性。结论:两个菌种急性攻毒试验结果表明属于无毒物质,安全性比较高。
|
| 关 键 词： | 嗜酸乳杆菌 枯草芽孢杆菌 益生菌 安全性 |
On Security of Lactobacillus Acidophilus LB10.16 and Bacillus Subtilis BS7.29 |
| |
| LI Jun-xun,GAO Jie,CHEN Kun,ZHANG Tong-cun,DU Lian-xiang.On Security of Lactobacillus Acidophilus LB10.16 and Bacillus Subtilis BS7.29[J].Progress in Modern Biomedicine,2011,11(1):22-25. |
| |
| Authors: | LI Jun-xun GAO Jie CHEN Kun ZHANG Tong-cun DU Lian-xiang |
| |
| Institution: | 1(1 Tianjin Key Laboratory of Industrial Microbiology,College of Biotechnology,Tianjin University of Science and Technology,Tianjin 300222,China;2 Biological sciences college of Taishan University Taian Shandong 271000,China) |
| |
| Abstract: | Objective: To investigate the security of lactobacillus acidophilus LB10.16 and bacillus subtilis BS7.29,in order to provide the technical support for the application.Method: Test methods including mice irrigation suits,acute attack poison,intraperi-toneal injection and mice biggest tolerance dose,acute attack toxicity test were applied to investigate the security of bacillus subtilis BS7.29 and lactobacillus acidophilus LB10.16.Results: The small intestinal vermiculation and intestinal peristalsis could be... |
| |
| Keywords: | Lactobacillus acidophilus Bacillus subtilis Probiotics Security |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
