参芎葡萄糖注射液联合脑蛋白水解物治疗急性脑梗塞的疗效及对神经功能缺损和血液流变学的影响

目的:探析参芎葡萄糖注射液与脑蛋白水解物联合治疗急性脑梗塞患者的临床疗效和对神经功能、血液流变学的影响。方法:入选急性脑梗患者130例,随机分为两组各65例。对照组在常规治疗基础上使用脑蛋白水解物治疗,治疗组在常规治疗基础上不仅使用脑蛋白水解物,还加用参芎葡萄糖注射液治疗,比较两组患者的临床效果、神经功能缺损评分改变和血液流变学情况。结果:治疗组有效率显著高于对照组(P0.05);神经功能缺损评分治疗后均有下降,但治疗组下降幅度更大(P0.05);治疗组红细胞压积、血小板聚集率和纤维蛋白原均显著下降(P0.05),且同期相比,治疗组纤维蛋白原和红细胞压积下降幅度显著优于对照组(P0.05)。结论:参芎葡萄糖注射液与脑蛋白水解物联合治疗急性脑梗塞患者疗效确切,安全可靠,值得临床推广。

Efficacy of Shenxiong Glucose Injection Combined with Brain Protein Hydrolyzate in Acute Cerebral Infarction and its Impact on Neurological Deficits and Hemorheology

Objective:To investigate the effect of Shenxiong glucose injection combined brain protein hydrolyzate in the treatment of acute cerebral infarction and its impact on neurological deficits and hemorheology.Methods:130 cases of patients with acute cerebral infarction were selected and randomly divided into two groups (65 cases for each group). The Control group was treated using brain protein hydrolyzate on the basis of conventional therapy, and the treatment group was given Shenxiong glucose injection therapy besides brain protein hydrolyzate, clinical results, neurological deficit scores changes and blood rheology of the two groups of patients were compared.Results:The effective rate of the treatment group was significantly higher than that of the control group (P <0.05). Neurological deficit scores of the two groups decreased after treatment, but there was a larger decline in the treatment group (P <0.05). The hematocrit, platelet aggregation and fibrin former of the treatment group significantly decreased (P <0.05), in addition, the decrease in fibrinogen and hematocrit was larger in the treatment group than in the control group (P <0.05).Conclusion:Shenxiong glucose injection combined with brain protein hydrolyzate is effective, safe and reliable in the treatment of acute cerebral infarction and is worthy of promotion