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奥氮平与碳酸锂分别联合丙戊酸钠治疗双相障碍躁狂发作 的临床疗效比较
引用本文:阿依夏木·伊不拉音,艾尼瓦尔·拜克热买买提热厦提·吐尔逊王丽萍.奥氮平与碳酸锂分别联合丙戊酸钠治疗双相障碍躁狂发作 的临床疗效比较[J].现代生物医学进展,2011,11(10):1947-1949.
作者姓名:阿依夏木·伊不拉音  艾尼瓦尔·拜克热买买提热厦提·吐尔逊王丽萍
作者单位:新疆维吾尔自治区乌鲁木齐市第四人民医院精神科,新疆,乌鲁木齐,830002
摘    要:目的:比较奥氮平与碳酸锂分别联合丙戊酸钠治疗双相障碍躁狂发作的临床疗效,探讨提高双相障碍躁狂发作临床疗效的药物治疗方案。方法:选择双相障碍躁狂发作患者90例,随机均分为A组与B组,A组给予奥氮平联合丙戊酸钠治疗,B组给予碳酸锂联合丙戊酸钠治疗,比较两组患者治疗第2周、第4周、第6周躁狂量表(BRMS)评分、副反应量表(TESS)评分和治疗第6周的临床疗效。结果:两组患者在上述方面比较,差异均具有统计学意义(P<0.05),A组临床疗效好于B组。结论:药物治疗双相障碍躁狂发作时,应选择奥氮平联合丙戊酸钠治疗方案,可提高临床疗效,减少用药后副反应。

关 键 词:奥氮平  丙戊酸钠  双相障碍躁狂发作  临床疗效

Clinical Efficacy Comparison of Olanzapine and Lithium Carbonate Respectively Combined with Sodium Valproate for Bipolar Disorder ManicEpisodes
Ayixiamu·yibulaiyin,Ainiwaer·baikeer,Maimaitierxiati·turxun,WANG Li-ping.Clinical Efficacy Comparison of Olanzapine and Lithium Carbonate Respectively Combined with Sodium Valproate for Bipolar Disorder ManicEpisodes[J].Progress in Modern Biomedicine,2011,11(10):1947-1949.
Authors:Ayixiamu·yibulaiyin  Ainiwaer·baikeer  Maimaitierxiati·turxun  WANG Li-ping
Institution:(Urumqi fourth people’s hospital,Psychiatric Department,Xinjiang Uygur Autonomous Region 830002,China)
Abstract:Objective:To compare the clinical efficacy of olanzapine and lithium carbonate combined sodium valproate in treatment of bipolar disorder manic episodes and research the drug treatment programs to improve the recent clinical efficacy.Method:Collect 90 bipolar disorder manic episodes patients,45 patients were divided into A group treated by olanzapine combined sodium valproate,45 patients were divided into B group treated by lithium carbonate combined sodium valproate,then compare the BRMS score and TESS sco...
Keywords:Olanzapine  Sodium valproate  Bipolar disorder manic episodes  Clinical efficacy  
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