腹膜透析病人的预后影响因素

在我国,终末期肾脏病的发病率逐年增加,相应地,腹膜透析病人的数量也在不断增长。明确腹膜透析病人预后的影响因素是临床医师亟待解决的重要课题。尿毒症毒素的积蓄可对腹膜透析病人的心血管系统产生不良作用,影响病人的生活质量。腹膜透析充分性的相关指标对于预测病人的生存率也有一定的指导意义。此外,腹膜炎的发生可使超滤量明显下降,增加病人的死亡率。合并症可能通过加重病人的营养不良状态、促进炎症水平,影响病人的预后。因此,重视病人的尿毒症毒素水平、透析充分性指标与合并症情况,积极防治腹膜炎,将有助于改善腹膜透析病人的预后。

Prognostic Factors of Peritoneal Dialysis Patients

ABSTRACT: In China, the incidence of end-stage renal disease was increasing year by year, and the number of peritoneal dialysis patients was also increasing. It was an important issue which was urgently to be solved by clinicians to clarify the prognostic factors of peritoneal dialysis patients. The accumulation of uremic toxins can have adverse effects on the cardiovascular system of peritoneal dialy- sis patients and affect their quality of life. The correlative indexes of peritoneal dialysis adequacy also had certain guiding significance for predicting patients'' survival rate. In addition, the occurrence of peritonitis can significantly reduce the ultrafiltration and increase the mor- tality. The complication may affect the patient''s prognosis by aggravating the malnutrition state and promoting inflammation. Therefore, paying attention to the level of uremia toxin, dialysis adequacy index and complications, and actively preventing and treating peritonitis will help improve the prognosis of peritoneal dialysis patients.