神经源性心脏损伤的研究进展

神经源性心脏损伤是指各种急性脑损伤患者出现的类似急性心肌损伤的临床症状,临床表现包括心电图异常、心肌酶升高、室壁运动功能障碍等。主要机制为颅脑病损伤影响自主神经的高级中枢丘脑下部时导致的神经系统功能紊乱及体液障碍。神经源性心脏损伤的发病率较高,且与患者住院时间延长和病死率增高相关。本文详细阐释了神经源性心脏损伤的临床表现、发病机制、预防及治疗,期望有助于临床诊断和科学研究。以期降低患者的死亡率,改善和提高患者的生活质量。

A Review of Neurocardiogenic Injury

ABSTRACT: Neurocardiogenic injury is defined as clinical symptoms which are similar with acute myocardial injury, occurring af- ter various types of acute brain injury. The typical spectrum of clinically observed abnormalities includes electrocardiogram, myocardial enzyme, ventricular wall motion dysfunction. The mechanism includes the dysfunction of nervous system and humoral disturbance in the lower part of the superior central hypothalamus, which affects the autonomic nerve. The occurrence of neurocardiogenic injury is related to the length of hospital stay and increases the risk of death. This review summarizes the possible clinical manifestation, mechanisms, prevention and treatment of neurocardiogenic injury, and it is expected to be helpful to clinical diagnosis and scientific research and con- tributes to reduce the mortality and improve the quality of patients.