经口激光显微手术治疗声门型喉癌的研究进展

经口激光显微手术(transoral laser microsurgery,TLM)应用于声门型喉癌(glottic carcinoma,GC)具有显著的优越性:安全有效,局部复发率低,喉保留率高,实现了GC的微创治疗。大量的研究表明TLM应用于早期GC的疗效与放射治疗和喉裂开术相似。因其不但损伤更小,更加精确,而且患者术后生活质量更好,为早期GC的首选治疗方式。目前将TLM推广应用到中晚期GC、前联合喉癌以及挽救放疗或TLM后早期复发性GC的治疗中,可能为有效保留喉部功能的治疗方式,但是国内相关的文献报道较少,较多的报道了开放性手术仍是GC主要的治疗方式。因此,本文就TLM治疗GC的现状、手术疗效、优越性、应用前景等方面做一综述,进一步研究及认识TLM对GC的治疗有非常重要的临床应用价值。

The Review of Transoral Laser Microsurgery in Glottic Carcinoma

Transoral laser microsurgery (TLM) has realized the minimally invasive treatment of glottic carcinoma (GC), which has the significant advantages: safety, effectiveness, low rate of local recurrence, and high rate of larynx preservation. Many researches showed that the results of TLMfor early GC appear to be comparable to those of radiotherapy and laryngofissure. It is recommended that TLMis the first choice for early GC, for which is not only less invasive, more precise and more functional, but also can provide a better quality of life. TLMmay be a curative organ-preserving treatment for advanced GC, anterior commissure GC, salvage early recurrent GC after radiotherapy or TLM, however, there are limited domestic literature reported, more have reported that the open surgical approaches is still the main treatment of GC. Therefore, the article reviews the recent clinical researches on TLMincluding status, effects, advantages and prospects in GC, further study and understanding TLMfor the treatment of GC provide important clinical application value.