无功能垂体瘤的术后评估

垂体瘤是常见的颅内良性肿瘤,患病率高,预后较好。在我国,其发病率仅次于胶质瘤和脑膜瘤。无功能垂体瘤约占垂体瘤22.5%,手术是其首选的治疗方式,以解除肿瘤的占位效应,减少对正常垂体组织的压迫。然而手术本身可能引起垂体功能减退,术后应对患者垂体功能的监测并予以处理。同时,由于手术及患者个体身体、心理原因,患者术后的生活质量也越来越受到重视。本文综述了无功能垂体瘤患者术后各内分泌轴功能的临床检测方法,以帮助临床医生对术后患者的垂体功能进行评估并重建;同时对术后患者生活质量的评估加以讨论,帮助指导患者恢复生理及心理健康。

Postoperative Evaluation of Non-functioning Pituitary Adenomas

ABSTRACT: Pituitary adenoma is a common benign intracranial tumor with high prevalence and good prognosis. In our country, the incidence rate is only second to glioma and meningioma. Nonfunctioning pituitary adenoma accounts for about 22.5 % of pituitary adenoma, and the surgery is the top priority which can remove the tumor occupying effect to reduce the oppression of normal pituitary tissue. However, the operation itself may cause pituitary dysfunction, so the postoperative monitoring and corresponding treatment is essential. At the same time, due to the surgery and patients'' physical, psychological reasons, the postoperative quality of life also has been paid more and more attention. This article reviewed the clinical detection methods to evaluate the endocrine function, which may help surgeons evaluate and reconstruct patients'' pituitary function. Meanwhile, the evaluation of quality of life was also discussed, which may guide the recovery of physical and psychological health.