阴道镜直视宫颈多点活检与传统宫颈活检在宫颈疾病诊断中的应用价值比较

目的:探讨阴道镜直视宫颈多点活检与传统宫颈活检对宫颈疾病诊断的临床应用及影响因素研究。方法:选择2015年5月至2016年3月我院妇科收治的宫颈疾病患者86例,按照随机数表法,将患者分为对照组和研究组,每组43例。对照组患者进行常规的宫颈活检,研究组患者采用阴道镜直视宫颈多点活检。对比两种检查方法与病理检查结果的检出率,并比较两种检查方法的漏诊率,另外考察影响阴道镜直视宫颈多点活检漏诊率的相关因素。结果:与病理检查结果相比,除宫颈炎和宫颈癌外,研究组对其他类型宫颈疾病的检出率及总检出率明显高于对照组(P0.05);除宫颈癌外,研究组对各种宫颈疾病的漏诊率与对照组相比明显下降(P0.05);年龄超过50岁,高级别的CIN类型、标本个数的减少及宫颈微小病变都可能升高阴道镜直视宫颈多点活检漏诊率。结论:与传统宫颈活检相比,阴道镜直视宫颈多点活检对宫颈疾病的诊断具有较高的诊断率,并且漏诊率较低,可以适当增加活检的样本个数来降低漏诊率,从而尽早发现并进行有效治疗,值得在临床上推广应用。

Application Value of Cervical Multi-point Biopsy under Colposcopy Compared with Routine Cervical Biopsy in Diagnosis of Cervical Disease

Objective:To explore the clinical application of cervical multi-point biopsy under colposcopy compared with routine cervical biopsy in the diagnosis of cervical disease and influencing factors.Methods:Selected 86 cases of patients with cervical disease admitted in department of gynaecology of our hospital from May 2015 to March 2016, and were divided into control group and research group according to the randomnumber table method, with 43 cases in each group. The patients in control group were treated with routine cervical biopsy, while the patients in research group were treated by cervical multi-point biopsy under colposcopy. Compared the relevance ratio of two kinds of methods and pathologic examination results, andcompared the omission diagnostic rate of two methods. In addition, explored the related factors of missed diagnosis of cervical multi-point biopsy under colposcopy.Results:Compared with pathologic examination results, except cervical disease and cervical cancer, the detection rate and total detection rate of other types of cervical disease in research group were significantly higher than those of control group (P<0.05); In addition to the cervical cancer, the missed diagnosis rate of cervical disease of research group significantlydecreased comparedwith the control group (P<0.05);Aged over 50, high-level CIN types, the decreased of number of specimens and cervical small lesions were likely to rise the missed diagnosis rate of cervical multi- point biopsy under colposcopy.Conclusion:Compared with the routine cervical biopsy, cervical multi-point biopsy under colposcopy in the diagnosis of cervical disease has high diagnostic rate and lowmissed diagnosis rate. We can appropriately increase number of biopsy samples to reduce the missed diagnosis so that cervical disease is treated by early detection and effective treatment.It is worth popularization and application in clinic.