腹腔镜肾癌根治术治疗肾癌的疗效观察

目的:观察腹腔镜肾癌根治术治疗肾癌的疗效。方法:选取2013年12月~2015年12月于我院诊治的肾细胞癌并行肾癌根治术患者70例,其中42例患者行腹腔镜肾癌根治术,纳入微创组;28例患者行开放性肾癌根治术,纳入对照组。比较两组患者围手术期情况、术后第3天炎症指标与肾功能、围术期并发症。结果:与对照组相比,微创组患者手术时间、住院时间、手术切口较短,术后下床走动时间、术后停止禁食时间较早,手术出血量、手术费用较少(P0.001)。与对照组相比,微创组患者WBC、CRP水平较低(P0.001)。微创组患者围术期总并发症发生率为4.8%,低于对照组(21.5%),差异有统计学意义(x~2=4.610,P=0.032)。结论:腹腔镜肾癌根治术治疗肾癌较开放性肾癌根治术有疗效佳、安全性好、术后恢复快及并发症少的优势,值得临床推广。

Observation of Curative Effect of Laparoscopic Radical Nephrectomy in Treatment of Renal Carcinoma

ABSTRACT Objective: To observe the curative effects of laparoscopic radical nephrectomy in the treatment of renal carcinoma. Methods: A total of 70 patients who had renal cell carcinoma and underwent radical nephrectomy in our hospital between December 2013 and December 2015 were selected in his study. 42 patients who underwent laparoscopic radical nephrectomy were taken into the minimally invasive group, while 28 patients who underwent open radical nephrectomy were taken into the control group. Perioperative situation, inflammation index and renal function at 3d after operation and perioperative complication of patients were compared between the two groups. Results: Patients in the minimally invasive group had shorter operation time, hospitalization time and incision, earlier time of out-of-bed activity and time of stop fasting after operation, less bleeding volume and operation cost than those in the control group (P<0.001). Moreover, patients in the minimally invasive group had lower level of WBC and CRP than those in the control group (P<0.001). The overall perioperative complication rate of the minimally invasive group was 4.8%, also lower than that of control group (21.5%), and the difference was statistically significant (x₂=4.610, P=0.032). Conclusion: Laparoscopic radical nephrectomy in treating renal carcinoma had advantages of better curative effects, much safer, more rapid postoperative recovery and less complications, as com- pared with open radical nephrectomy. Thus, it is worthy of clinical promotion.