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神经节苷脂联合α-硫辛酸治疗糖尿病神经源性膀胱临床观察
引用本文:李振兴,谭万寿,周斌,金铃,颜勇华.神经节苷脂联合α-硫辛酸治疗糖尿病神经源性膀胱临床观察[J].现代生物医学进展,2011,11(16):3149-3151.
作者姓名:李振兴  谭万寿  周斌  金铃  颜勇华
作者单位:湖南省邵阳市中心医院内分泌科 湖南邵阳 422000
摘    要:目的:观察α-硫辛酸、神经节苷脂联合治疗糖尿病神经源性膀胱的临床疗效。方法:60例2型糖尿病神经源性膀胱患者,随机分为α-硫辛酸治疗对照组、神经节苷脂治疗对照组,联合治疗组,疗程30d,观察症状体征及治疗前后B超膀胱残余尿量症状的变化,比较不同方案的疗效。结果:α-硫辛酸治疗对照组有效率90%,神经节苷脂治疗对照组有效率90%,联合治疗组有效率95%两组间无统计学差异(P>0.05),但3组的治愈率分别为90.0%、50.0%、60.0%,治疗组的治愈率高于两个对照组,有统计学差异(P<0.05)。结论:α-硫辛酸和神经节苷脂联合治疗糖尿病神经源性膀胱有较好的临床疗效,值得临床推广。

关 键 词:糖尿病  神经源性膀胱  α-硫辛酸  神经节苷脂

Clinical Observation on Lipoic acid and Ganglioside in Treating Diabetic Neurogenic Bladder
LI Zhen-xing,TAN Wan-shou,ZHOU Bin,JIN Ling,YAN Yong-hua.Clinical Observation on Lipoic acid and Ganglioside in Treating Diabetic Neurogenic Bladder[J].Progress in Modern Biomedicine,2011,11(16):3149-3151.
Authors:LI Zhen-xing  TAN Wan-shou  ZHOU Bin  JIN Ling  YAN Yong-hua
Institution:LI Zhen-xing,TAN Wan-shou,ZHOU Bin,JIN Ling,YAN Yong-hua (Department of Endocrinology,Shaoyangi central hospital Shaoyani Hunan 422000)
Abstract:Objective:The studywas designed to assess the role of lipoic acid and ganglioside in treating diabetic neurogenic bladder.Methods:Sixty patients with type 2 diabetes and diabetic neurogenic bladder were treated with lipoic acid and ganglioside for 30 days,and the postvoiding residue of bladder measured by ultrasonogram were compared before and after therapy.Results:The postvoiding residue of bladder after therapy were significantly decreased than those before therapy.Comparison of the efficacy of different ...
Keywords:Type 2 diabetes  Diabetic neurogenic bladder  Lipoic acid  Ganglioside  
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