早期肠内营养和肠外营养对ICU中重症肺炎患者预后的影响

目的:研究早期肠内和肠外营养对ICU中重症肺炎患者预后的影响。方法:选取2013年1月-2014年1月我院重症医学科60例重症肺炎患者随机分为肠内营养组30例(enteral nutrition,EN组)和完全肠外营养支持组30例(total parenteral nutrition,TPN组),经过营养支持治疗后,将两组的免疫、营养以及有创机械通气的时间等指标进行比较。结果:肠内营养组与肠外营养组对比发现,在第5天、第10天EN组血清免疫球蛋白和T细胞亚群细胞数显著升高(P0.05);血红蛋白(HGB)、白蛋白(ALB)和血清前白蛋白(PAB)明显升高(P0.05);有创机械通气时间缩短(P0.05),差异具有统计学意义。结论:ICU中重症肺炎应选择肠内营养支持方式,肠内营养能有效的改善营养状态,并能改善患者的免疫功能,减少有创机械通气时间。

Effact of Early Enteral Nutrition and Total Parenteral Nutritionin the Treatment for Patients with Severe Pneumonia in ICU

Objective:To evaluate the effact of early enteral nutrition and total parenteral nutritionin support for the treatment of patients with severe pneumonia in ICU;Methods:60 cases of patients with severe pneumonia were collected from january 2013 to January 2014 in our hospital. They were randomly divided into two groups, enteral nutrition group of 30 cases(EN group) and parenteral nutrition group of 30 cases(TPN group). The immune status, nutritionan status and the time of ventilation were detected and comparison before intertion on the fifth days, tenth day after intervention.Results:Serum immunoglobulin IgA, IgG, IgMlevels and perigperal blood T lympgocyte subsets in EN group were hiher than TPN (P<0.05). Hemoglobin and albumin levels were significantly higher than the parenteral nutrition group after the tenth day of treatment (P<0.05). The time of ventilation of EN group were shorter than TPN group.Conclusion:Enteral nutrition support therapy in the treatment of patients with severe pneumonia was crucially benefic in promoting the rehabilitation of patients.