胸前壁乳晕径路内镜甲状腺手术对免疫及甲状腺激素影响的 临床对照研究

目的:探究内镜下甲状腺手术经胸前壁乳晕径路对机体内免疫系统、甲状腺激素分泌影响情况。方法:对照组随机选取我院2010年5月~2011年5月住院行甲状腺传统手术治疗患者20例,同时随机选取广州暨南大学第一附属医院普外科经胸前壁乳晕径路手术治疗患者20例进行对照研究。结果:内镜下治疗后机体早期体液免疫、细胞免疫受一定程度抑制。内镜治疗下早期细胞免疫度抑制较开放手术轻(P<0.05)结论:胸前壁乳晕径路内镜甲状腺手术对免疫及甲状腺激素均有影响,把握其中变化趋势可更好的指导临床治疗。

Clinical Controlled Study on the Effect of \Chest Wall Areola Approach Endoscopic Thyroid Operation on Immune and Thyroid Hormone

Objective: To investigate the effects of endoscopic thyroidectomy operation via anterior chest wall areola approach on the body immune system and secretion of the thyroid hormone.Methods: 20 cases of patients who hospitalized in our hospital during May 2010 and May 2011 and treated with traditional thyroid operation were randomly selected as the control group.20 cases of endoscopic thyroidectomy via anterior chest wall areola approach from the first affiliated hospital of Jinan University were randomly selected as the observation group.Results: After endoscopic thyroidectomy treatment,early humoral immunity and cellular immunity of organism were restrained to a certain degree.Early cell immunity suppression by endoscopic treatment was lighter than by the open operation(P<0.05).Conclusion: Chest wall areola approach endoscopic thyroid operation had effect on both immune and thyroid hormones.Grasp of the changing trends can better guide clinical treatment.