婴儿腹痛与家族性偏头痛的相关性研究

目的:研究家族性偏头痛对婴儿腹痛的影响及其相关性。方法:112例婴儿腹痛患儿为腹痛组,97例同期就诊非婴儿腹痛及头痛患儿为对照组,对所有患儿的一、二级及三级亲属进行问卷调查,然后对有偏头痛的亲属用统一的标准进行诊断,最后对两组患儿及其亲属的发病率进行对比分析。结果:20例(17.86%)婴儿腹痛患儿有家族性偏头痛,对照组6例(6.19%)患儿有家族性偏头痛,家族性患偏头痛的患儿比例在两组之间有显著差异(P<0.05);婴儿腹痛患儿的亲属诊断为偏头痛有85例,占本组调查总人数的16.93%,对照组患儿偏头痛亲属共有17例,占调查总人数的2.37%,两组患儿亲属患偏头痛的发病率有显著差异(P<0.05);患儿亲属患偏头痛种类的比较:腹痛组有家族性偏瘫型偏头痛和儿童腹型偏头痛,对照组没有;除散发性偏瘫型偏头痛的在两组的差异有统计学意义(P<0.05),其他种类的偏头痛没有显著差异。结论:有家族性偏头痛史的婴儿腹痛发生率高于正常人,婴儿腹痛与家族性偏头痛的发生率相关,与偏头痛的种类也可能有关。

Research on the Relationship between Infantile Colic and Familial Migraine

Objective: To explore the relationship between infantile colic and Familial Migraine.Methods: There are 112 Infants with infantile colic as infantile colic group,the control group was composed of 97 cases of Infants over the same time diagnosed as no-infantile colic.A questionnaire survey was conducted among the first-degree relatives,second degree relatives and third degree relative of the Infants in the two groups.then the family members of the migraine were diagnosed with unification standard,Finally Infants and their relatives in two groups of were compared and analyzed.Results: 20 cases(17.86%) infants with infantile colic had familial migraine,6 cases(6.19%) infants in the control group had familial migraine,there was significant difference(P < 0.05) between the two groups in proportion of infants with infantile colic and familial migraine.85 cases relatives of the infantile colic group were diagnosed with migraine,accounting for 16.93% of the total number investigated in the group.17 cases relatives of the control group were diagnosed with migraine,accounting for 2.37% of the total number investigated in the group.The incidence of relatives suffering from migraine in the two groups had significant differences(P <0.05).Variety comparison of kinds of migraine in the relatives of the two groups:familial hemiplegic migraine and abdominal migraine in children were found in infantile colic group,but not found in the control group.Except for sporadic hemiplegic migraine(P < 0.05),other kinds of migraine have no significant difference in the two groups of relatives.Conclusions: Incidence of infantile colic among the infants with familial migraine history was higher than that among the infants without familial migraine history.The incidence of infantile colic was associated with that of familial migraine,and the kinds of migraine may also be relevant to infantile colic.