蛋白多肽类药物制剂的研究进展

相对于其他的给药途径,蛋白质多肽类药物的口服、经鼻、肺部给药途径更具可行性和商业价值。利用制剂学方法可提高蛋白质多肽类药物生物利用度。通过蛋白多肽类给药系统的评价,对近年来国内外此类药物在剂型、体内外稳定性及生物利用度等方面的研究进展予以综述。

Progress in Protein Polypeptides Preparations

Compared with other routes of administration,the route of administration of protein peptide drugs including oral,nasal,pulmonary is more feasible and commercial value.The pharmaceutics methods can improve their bioavailability.This paper evalu-ated the protein peptide drug delivery systems and reviewed the drugs in vivo stability and bioavailability research progress at home and abroad in recent years.